Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul 15;12(1):1239.
doi: 10.1038/s41597-025-05510-x.

Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis

Yingxin Liu #  1 , Gregory Y H Lip  2   3 , Jingyi Zhang #  1 , Xuerui Bai  4 , Jianfeng Li  5 , Lehana Thabane  6   7   8 , Harriette G C Van Spall  6   9 , Guowei Li #  10   11
Affiliations

Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis

Yingxin Liu et al. Sci Data. .

Abstract

Many cardiovascular disease (CVD) journals request data sharing statements upon trial report submission, but their compliance in publishing these statements remains unclear. We therefore performed a quantitative analysis to evaluate the current practice of the publications of data sharing statements in clinical trials by CVD journals, which included 78 CVD journals that published clinical trials from Jan 2019 to Dec 2022 and had data sharing statement request. Multivariable logistic regression analysis was used to examine the association between journal characteristics and journals' publications of statements. We also ran an online qualitative survey by sending anonymous questionnaires to editors-in-chief from CVD journals for their opinions on journals' publications of statements, trying to further explore why the journals did not publish statements. Their perspectives could provide in-depth information on and new insights into promoting publications of data sharing statements. This quantitative and qualitative analysis assessing the current practice of publishing data sharing statements by CVD journals, may generate new evidence to promote the actual data sharing and transparency in CVD trials.

PubMed Disclaimer

Conflict of interest statement

Competing interests: G.Y.H.L. has served as a consultant and speaker for BMS/Pfizer, Boehringer Ingelheim, and Daiichi-Sankyo. No fees have been received directly or personally. All other authors have declared no conflicts of interest.

Figures

Fig. 1
Fig. 1
Flow diagram showing the selection of journals and editors-in-chief for this quantitative and qualitative study.
Fig. 2
Fig. 2
Multivariable logistic regression analysis results for the association between journal characteristics and publication of data sharing statements.
Fig. 3
Fig. 3
Survey results of editors-in-chief of the included CVD journals regarding publications of data sharing statements in clinical trials.
See this image and copyright information in PMC

References

    1. Taichman, D. B. et al. Sharing Clinical Trial Data: A Proposal From the International Committee of Medical Journal Editors. JAMA315(5), 467–468 (2016). - PubMed
    1. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet403(10440), 2133–2161 (2024). - PMC - PubMed
    1. Bauchner, H., Golub, R. M. & Fontanarosa, P. B. Data Sharing: An Ethical and Scientific Imperative. JAMA315(12), 1237–1239 (2016). - PubMed
    1. Warren, E. Strengthening Research through Data Sharing. N Engl J Med375(5), 401–403 (2016). - PubMed
    1. Pisani, E. et al. Beyond open data: realising the health benefits of sharing data. BMJ355, i5295 (2016). - PMC - PubMed