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[Preprint]. 2025 Jun 26:2025.06.17.660217.
doi: 10.1101/2025.06.17.660217.

Neuromechanical Simulation with NEURON and MuJoCo

Neuromechanical Simulation with NEURON and MuJoCo

Chris Fietkiewicz et al. bioRxiv. .

Abstract

In computational neuroscience, simulation platforms generally do not have adequate tools to model the brain, body and environment simultaneously. We demonstrate a method for simulating neuromechanical models using a novel combination of widely used software platforms: NEURON and MuJoCo. Different neural models are used to control a realistic musculoskeletal model in both open-loop and closed-loop configurations. Three models are presented: (1) an open-loop model using simple spiking neurons from the NEURON model library; (2) an open-loop model using realistic, spiking motoneurons; and (3) a closed-loop central pattern generator with feedback from the physics engine.

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