Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul 16;20(7):e0324740.
doi: 10.1371/journal.pone.0324740. eCollection 2025.

Integrating augmented reality virtual patients into healthcare training: A scoping review of learning design and technical requirements

Affiliations

Integrating augmented reality virtual patients into healthcare training: A scoping review of learning design and technical requirements

Farshid Chahartangi et al. PLoS One. .

Abstract

Augmented reality (AR) enables users to view the real world with enhanced digital information, making it a transformative tool in education. Virtual patients (VPs) technology is also defined as "a specific type of computer-based application that simulates real-world clinical scenario. AR and VPs offer interactive and immersive learning experiences, with AR enhancing the understanding of complex concepts and VPs providing hands-on practice in clinical scenario. This scoping review aims to identify an integrated learning design framework and the technical requirements for augmented reality-based virtual patient Simulation in healthcare professions education. This study employed a scoping review methodology that adhered to the PRISMA-ScR checklist and the Joanna Briggs Institute (JBI) guidelines, conducted between September and October 2024. The review covered six reputable databases: MEDLINE (PubMed), Science Direct (Elsevier), Web of Science (Clarivate), Cochrane library, ERIC, Scopus. A comprehensive search yielded 924 potential studies. Articles were selected via a two-stage screening process, involving title/abstract and full-text reviews based on predefined inclusion criteria. Disagreements were resolved through consultation, resulting in 27 studies being included. Eligible studies focused on augmented reality (AR)-based virtual patient (VP) technology in healthcare education, encompassing observational, quasi-experimental, and descriptive designs. Exclusions comprised grey literature, irrelevant studies, non-full-text articles, and non-AR/VP-focused research (e.g., standalone virtual reality). Various design approaches were employed, including situated learning, experiential learning, and the ADDEI model. The technical foundations of these studies were diverse, with Unity, UTTIME and PalpSim being commonly used software platforms. It is recommended that future studies thoroughly investigate each of these design framework and the technical requirements of VPAR, examining them in greater detail from various cultural, economic, social, and emotional perspectives. Tackling these problems will be a crucial stride towards enhancing and optimizing education for healthcare professions education.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. PRISMA-SCR flow diagram of the search and study selection process for virtual patient and augmented reality integration in health care professions education.
Fig 2
Fig 2. Geographical distribution chart of studies.
Fig 3
Fig 3. Diagram of participants (students) in studies.
Fig 4
Fig 4. Chart of study types.
Fig 5
Fig 5. Conceptual framework of virtual patient augmented reality (VPAR).

Similar articles

References

    1. Khoshbakht-Pishkhani M, Javadi-Pashaki N, Esfandi NA, Koodakani MB, Maroufizadeh S, Madani AH. The effect of educational application in nursing internship clinical training on cognitive and functional skills and students’ satisfaction. BMC Nurs. 2024;23(1):381. doi: 10.1186/s12912-024-01954-5 - DOI - PMC - PubMed
    1. Al-Dahir S, Bryant K, Kennedy KB, Robinson DS. Online virtual-patient cases versus traditional problem-based learning in advanced pharmacy practice experiences. Am J Pharm Educ. 2014;78(4):76. doi: 10.5688/ajpe78476 - DOI - PMC - PubMed
    1. Brunzini A, Papetti A, Messi D, Germani M. A comprehensive method to design and assess mixed reality simulations. Virtual Reality. 2022;26(4):1257–75. doi: 10.1007/s10055-022-00632-8 - DOI
    1. Alexander SM, Friedman V, Rerkpattanapipat PM, Hiatt WA, Heneghan JS, Hubal R, et al. Adapting Novel Augmented Reality Devices for Patient Simulations in Medical Education. Cureus. 2024;16(8):e66209. doi: 10.7759/cureus.66209 - DOI - PMC - PubMed
    1. Mosalanejad L, Ebrahimi AM, Tafvizi M, Zarifsanaiey N. A constructive blended approach to ethical reasoning: the impact on medical students’ reflection and learning. n.d.

Publication types

LinkOut - more resources