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Review
. 2025 Aug;45(3):367-385.
doi: 10.1016/j.iac.2025.04.005. Epub 2025 Jun 11.

Prevention and Management of Food Allergy in Infants

Mehr Mathew  1 , Katelyn H Wong  1 , Julia Shook Munoz  2 , Stephanie Leeds  3
Affiliations
Review

Prevention and Management of Food Allergy in Infants

Mehr Mathew et al. Immunol Allergy Clin North Am. 2025 Aug.

Abstract

Given the significant medical, economic, and psychosocial burden of food allergies, there is great interest in identifying effective strategies in food allergy prevention, diagnosis, and management as early as possible. Infants are a unique population regarding food allergy, in that there are significant opportunities for primary prevention or early treatment with hope of disease remission. Unique aspects of infant food allergy include age-specific signs and symptoms of reactions, distinct preparation needs for oral food challenges, as well as attention to nutritional requirements for growth and development.

Keywords: Early food introduction; Early oral immunotherapy; Food allergy prevention; Infant food allergy.

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Conflict of interest statement

Disclosure S. Leeds is a consultant for Regeneron and Linical. She also receives funding from Food Allergy Research and Education, United States (FARE). M. Mathew, K.H. Wong, and J.S. Munoz have no disclosures.