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Review
. 2025 Aug;29(3):431-452.
doi: 10.1016/j.cld.2025.03.002. Epub 2025 May 22.

Bacterial Infections Involving the Liver

Affiliations
Review

Bacterial Infections Involving the Liver

Alan Koff et al. Clin Liver Dis. 2025 Aug.

Abstract

A wide variety of bacterial pathogens have been demonstrated to cause hepatic infection, leading to a range of clinical manifestations, including subclinical hepatitis, liver abscess, cholestatic hepatitis, and rarely fulminant hepatic failure. These organisms exhibit different epidemiology; some are transmitted through inhalation, others by an insect vector or animal exposure. A patient's exposure history, combined with the clinical findings and presence of hepatic dysfunction, may provide clues to the underlying diagnosis and have prognostic implications. This section will review the most important or characteristic bacterial infections involving the liver, focusing on the patterns and severity of liver dysfunction and treatment.

Keywords: Bacterial hepatic infections; Granulomatous inflammation; Hepatitis; Liver; Transaminitis.

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Conflict of interest statement

Disclosure Authors have no financial disclosures related to this article.

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