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Case Reports
. 2025 Jul 17;18(7):e265728.
doi: 10.1136/bcr-2025-265728.

Hepatotoxicity induced by MK-677

Affiliations
Case Reports

Hepatotoxicity induced by MK-677

Era Cobani et al. BMJ Case Rep. .

Abstract

MK-677, a growth hormone secretagogue, is gaining popularity among performance-enhancing supplements. While its side effects include oedema, increased appetite and muscle pain, reports of hepatotoxicity are scarce. Here we present the case of an otherwise healthy man in his early 30s, who developed transaminitis after consuming MK-677 for 2 months before presentation. Liver function tests eventually returned to normal limits after stopping the supplement.

Keywords: General practice / family medicine; Liver disease; Nutrition; Vitamins and supplements.

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Conflict of interest statement

Competing interests: None declared.

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