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Editorial
. 2025 Jul 16;11(4):e200290.
doi: 10.1212/NXG.0000000000200290. eCollection 2025 Aug.

Valosin-Containing Protein Multisystem Proteinopathy and Myopathology

Werner Stenzel  1 , Hans H Goebel  1
Affiliations
Editorial

Valosin-Containing Protein Multisystem Proteinopathy and Myopathology

Werner Stenzel et al. Neurol Genet. .
No abstract available

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Conflict of interest statement

The authors report no relevant disclosures. Go to Neurology.org/NG for full disclosures.

Comment in

  • Muscle Biopsy Findings in Valosin-Containing Protein Multisystem Proteinopathy.
    Schiava M, Parkhurst Y, Henderson M, Polvikoski T, Valtcheva MV, Nishino I, Inoue M, Nishimori Y, Saito Y, Stojkovic T, Villar-Quiles RN, Romero NB, Evangelista T, Malfatti E, Souvannanorath S, Pegoraro E, Riguzzi P, Monforte M, Bortolani S, Torchia E, Sabatelli M, Tasca G, Straub V, Marini-Bettolo C, Guglieri M, Cetin H, Gelpi E, Klotz S, De Bleecker JL, Alonso-Jimenez A, Baets J, De Ridder W, De Jonghe P, Claeys KG, Thal DR, Bevilacqua JA, Luo S, Zhu W, Lin J, Papadimas G, Papadopoulos C, Zamba-Papanicolaou E, Xirou S, Pal E, Rodolico C, Kostera-Pruszczyk A, Kierdaszuk B, Kaminska A, Muelas N, Vilchez JJ, Domínguez-González C, Hernandez-Lain A, Alonso-Perez J, Nedkova-Hristova V, Aledo C, Oldfors A, Badrising UA, Kushlaf H, Lloyd TE, Ikenaga C, Alfano LN, Quinn CC, Walk D, Vorgerd M, Weihl C, Olivé M, Diaz-Manera J; VCP International Study Group. Schiava M, et al. Neurol Genet. 2025 Jul 16;11(4):e200265. doi: 10.1212/NXG.0000000000200265. eCollection 2025 Aug. Neurol Genet. 2025. PMID: 40678441 Free PMC article.

References

    1. Meyer H, Bug M, Bremer S. Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. Nat Cell Biol. 2012;14(2):117-123. doi: 10.1038/ncb2407 - DOI - PubMed
    1. van den Boom J, Meyer H. VCP/p97-Mediated unfolding as a principle in protein homeostasis and signaling. Mol Cell. 2018;69(2):182-194. doi: 10.1016/j.molcel.2017.10.028 - DOI - PubMed
    1. Ye Y. Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase. J Struct Biol. 2006;156(1):29-40. doi: 10.1016/j.jsb.2006.01.005 - DOI - PubMed
    1. Ju JS, Weihl CC. p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system. Autophagy. 2010;6(2):283-285. doi: 10.4161/auto.6.2.11063 - DOI - PMC - PubMed
    1. Dalal S, Hanson PI. Membrane traffic: what drives the AAA motor? Cell. 2001;104(1):5-8. doi: 10.1016/s0092-8674(01)00186-6 - DOI - PubMed

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