The Lancet One Health Commission: harnessing our interconnectedness for equitable, sustainable, and healthy socioecological systems

Andrea S Winkler¹, Christina Marie Brux², Hélène Carabin³, Carlos G das Neves⁴, Barbara Häsler⁵, Jakob Zinsstag⁶, Eric Maurice Fèvre⁷, Anna Okello⁸, Gabrielle Laing⁹, Wendy Elizabeth Harrison¹⁰, Anna K Pöntinen¹¹, Annalena Huber¹², Arne Ruckert¹³, Barbara Natterson-Horowitz¹⁴, Bernadette Abela¹⁵, Cécile Aenishaenslin¹⁶, David L Heymann¹⁷, Ernst Kristian Rødland¹⁸, Franck C J Berthe¹⁹, Ilaria Capua²⁰, James Sejvar²¹, Juan Lubroth²², Jukka Corander²³, Jürgen May²⁴, Laura Franziska Roth¹², Lian Francesca Thomas²⁵, Lucille Blumberg²⁶, Maria Knight Lapinski²⁷, Matthew Stone²⁸, Melvin Katey Agbogbatey²⁹, Ning Xiao³⁰, Osama Ahmed Hassan³¹, Osman Dar³², Peter Daszak³³, Renzo R Guinto³⁴, Sera Senturk¹², Sundeep Sahay³⁵, Thelma Alafia Samuels³⁶, Yngvild Wasteson³⁷, John H Amuasi³⁸

Affiliations

¹ Department of Neurology, Technical University of Munich University Hospital, and Center for Global Health, School of Medicine and Health, Technical University of Munich, Munich, Germany; Department of Community Medicine and Global Health, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
² Sustainable Health Unit, Faculty of Medicine, University of Oslo, Oslo, Norway.
³ Faculty of Veterinary Medicine and School of Public Health, University of Montreal, Montreal, QC, Canada.
⁴ European Food Safety Authority, Parma, Italy; Norwegian Veterinary Institute, Oslo, Norway.
⁵ Department of Pathobiology and Population Sciences, Veterinary Epidemiology, Economics and Public Health Group, The Royal Veterinary College, Hatfield, UK; Network for EcoHealth and One Health, Allschwil, Schwitzerland.
⁶ Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland.
⁷ Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; International Livestock Research Institute, Nairobi, Kenya.
⁸ Australian Centre for International Agricultural Research, Canberra, ACT, Australia; University of Edinburgh, Edinburgh, UK.
⁹ Network for EcoHealth and One Health, Allschwil, Schwitzerland; Unlimit Health, London, UK.
¹⁰ Unlimit Health, London, UK.
¹¹ Department of Biostatistics, University of Oslo, Oslo, Norway.
¹² Department of Neurology, Technical University of Munich University Hospital, and Center for Global Health, School of Medicine and Health, Technical University of Munich, Munich, Germany.
¹³ University of Ottawa, Ottawa, ON, Canada.
¹⁴ Harvard Medical School, Boston, MA, USA.
¹⁵ WHO, Geneva, Switzerland.
¹⁶ University of Montreal, Montreal, QC, Canada.
¹⁷ London School of Hygiene & Tropical Medicine, London, UK.
¹⁸ Norwegian Institute of Public Health and University of Oslo, Oslo, Norway.
¹⁹ World Bank, Washington, DC, USA.
²⁰ SAIS Europe, Johns Hopkins University, Bologna, Italy; University of Florida, Gainesville, FL, USA.
²¹ University of Pittsburgh, Pittsburgh, PA, USA.
²² Lubroth One Health Consultancies, Riety, Italy.
²³ Department of Biostatistics, University of Oslo, Oslo, Norway; Wellcome Sanger Institute, Parasites and Microbes, Hinxton, UK.
²⁴ Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; German Center for Infection Research, Hamburg, Germany.
²⁵ International Livestock Research Institute, Nairobi, Kenya; University of Edinburgh, Edinburgh, UK.
²⁶ National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa; Faculty of Veterinary Service, University of Pretoria, Pretoria, South Africa; University of Stellenbosch, Western Cape, South Africa; Right to Care, Centurion, South Africa.
²⁷ Department of Communication, Michigan AgBio Research, Michigan State University, East Lansing, MI, USA.
²⁸ World Organization for Animal Health, Paris, France; SPADE Solutions, Wellington, New Zealand.
²⁹ Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; Kumasi Center for Collaborative Research in Tropical Medicine, Kumasi, Ghana; Department of Global Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
³⁰ National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention and Shanghai Jiao Tong University School of Global Health, Shanghai, China.
³¹ Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
³² UK Health Security Agency, London, UK; Chatham House, Royal Institute of International Affairs, London, UK.
³³ Nature.Health.Global., Tallman, NY, USA.
³⁴ SIngHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, National University of Singapore, Singapore.
³⁵ Department of Informatics, University of Oslo, Oslo, Norway; Sustainable Healthcare Education, Oslo, Norway.
³⁶ The University of the West Indies, Kingston, Jamaica.
³⁷ Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
³⁸ Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; Kumasi Center for Collaborative Research in Tropical Medicine, Kumasi, Ghana; Department of Global Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. Electronic address: amuasi@kccr.de.

PMID: 40683291
DOI: 10.1016/S0140-6736(25)00627-0

Review

The Lancet One Health Commission: harnessing our interconnectedness for equitable, sustainable, and healthy socioecological systems

Andrea S Winkler et al. Lancet. 2025.

. 2025 Aug 2;406(10502):501-570.

doi: 10.1016/S0140-6736(25)00627-0. Epub 2025 Jul 16.

Authors

Affiliations

¹ Department of Neurology, Technical University of Munich University Hospital, and Center for Global Health, School of Medicine and Health, Technical University of Munich, Munich, Germany; Department of Community Medicine and Global Health, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
² Sustainable Health Unit, Faculty of Medicine, University of Oslo, Oslo, Norway.
³ Faculty of Veterinary Medicine and School of Public Health, University of Montreal, Montreal, QC, Canada.
⁴ European Food Safety Authority, Parma, Italy; Norwegian Veterinary Institute, Oslo, Norway.
⁵ Department of Pathobiology and Population Sciences, Veterinary Epidemiology, Economics and Public Health Group, The Royal Veterinary College, Hatfield, UK; Network for EcoHealth and One Health, Allschwil, Schwitzerland.
⁶ Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland.
⁷ Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; International Livestock Research Institute, Nairobi, Kenya.
⁸ Australian Centre for International Agricultural Research, Canberra, ACT, Australia; University of Edinburgh, Edinburgh, UK.
⁹ Network for EcoHealth and One Health, Allschwil, Schwitzerland; Unlimit Health, London, UK.
¹⁰ Unlimit Health, London, UK.
¹¹ Department of Biostatistics, University of Oslo, Oslo, Norway.
¹² Department of Neurology, Technical University of Munich University Hospital, and Center for Global Health, School of Medicine and Health, Technical University of Munich, Munich, Germany.
¹³ University of Ottawa, Ottawa, ON, Canada.
¹⁴ Harvard Medical School, Boston, MA, USA.
¹⁵ WHO, Geneva, Switzerland.
¹⁶ University of Montreal, Montreal, QC, Canada.
¹⁷ London School of Hygiene & Tropical Medicine, London, UK.
¹⁸ Norwegian Institute of Public Health and University of Oslo, Oslo, Norway.
¹⁹ World Bank, Washington, DC, USA.
²⁰ SAIS Europe, Johns Hopkins University, Bologna, Italy; University of Florida, Gainesville, FL, USA.
²¹ University of Pittsburgh, Pittsburgh, PA, USA.
²² Lubroth One Health Consultancies, Riety, Italy.
²³ Department of Biostatistics, University of Oslo, Oslo, Norway; Wellcome Sanger Institute, Parasites and Microbes, Hinxton, UK.
²⁴ Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; German Center for Infection Research, Hamburg, Germany.
²⁵ International Livestock Research Institute, Nairobi, Kenya; University of Edinburgh, Edinburgh, UK.
²⁶ National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa; Faculty of Veterinary Service, University of Pretoria, Pretoria, South Africa; University of Stellenbosch, Western Cape, South Africa; Right to Care, Centurion, South Africa.
²⁷ Department of Communication, Michigan AgBio Research, Michigan State University, East Lansing, MI, USA.
²⁸ World Organization for Animal Health, Paris, France; SPADE Solutions, Wellington, New Zealand.
²⁹ Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; Kumasi Center for Collaborative Research in Tropical Medicine, Kumasi, Ghana; Department of Global Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
³⁰ National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention and Shanghai Jiao Tong University School of Global Health, Shanghai, China.
³¹ Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
³² UK Health Security Agency, London, UK; Chatham House, Royal Institute of International Affairs, London, UK.
³³ Nature.Health.Global., Tallman, NY, USA.
³⁴ SIngHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, National University of Singapore, Singapore.
³⁵ Department of Informatics, University of Oslo, Oslo, Norway; Sustainable Healthcare Education, Oslo, Norway.
³⁶ The University of the West Indies, Kingston, Jamaica.
³⁷ Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
³⁸ Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; Kumasi Center for Collaborative Research in Tropical Medicine, Kumasi, Ghana; Department of Global Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. Electronic address: amuasi@kccr.de.

PMID: 40683291
DOI: 10.1016/S0140-6736(25)00627-0

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Conflict of interest statement

Declaration of interests ASW is affiliated with two institutions that hosted commission secretariats and to whom funding for the Commission was allocated from two funding sources (the University of Oslo, which received funding from UiO:Life Science, and the Technical University of Munich, which received funding from the German Federal Ministry of Education and Research). CMB, AH, and SSe received compensation for their time spent working on the Commission as employees of the two institutions that were allocated funds for the commission (CMB at the University of Oslo, and AH and SSe at the Technical University of Munich). AH also supported the I-DAIR Pandemic Scientific Working Group in the role of a One Health expert. JHA and RRG are members of the Lancet–Chatham House Commission on improving population health post COVID-19. JZ, JL, MS, DLH, OD, and OAH are co-authors on papers in the Lancet Series on One Health and Global Health Security. CGdN received three grants for One Health activities in the 36 months before the submission of this Commission (Norwegian Government Grant for the National Wildlife Health Surveillance Programme Helseovervåkingsprogrammet for vilt, Research Council of Norway Grant for the arrangement of a Norwegian One Health Conference in November, 2022, and Horizon Europe European Joint Programmes One Health Grant for the Norwegian Veterinary Institute 2018–23). CGdN also received payment for a talk (at the World One Health Congress in Singapore, November 2022) and support for participation in two meetings and conferences about One Health (One Health Conference of the University of Queensland in September, 2022, and Canadian Global 1 Health Network annual meeting in Montreal in June, 2022). CGdN also had unpaid roles in the Wildlife Disease Association (president, 2019–21), Wildlife Population Health Specialty of the European College of Zoological Medicine (chair, 2018–23), and the International Union for Conservation of Nature and Natural Resources Species Survival Commission on Wildlife Health (wildlife health specialist, 2018–23). EMF received grants for One Health research in the 36 months before this publication was submitted (from the Consultative Group for International Agricultural Research, UK Research and Innovation, and US Defense Threat Reduction Agency), as well as payment for a talk and support to attend a WHO meeting of relevance for One Health. EMF is also a member of the Senior Editorial Board for the CABI One Health Journal. AO received travel support from her institution, the Australian Centre for International Agricultural Research, to participate in a commission meeting. AR is funded by the Global One Health Network to coordinate and conduct research on One Health governance. JL is Chair of the International Working Group of the One Sustainable Health Forum (unpaid) and also coordinates and advises the Scientific Committee of the One Sustainable Health Forum (consultancy). JL received payment and travel support for speaking contributions to the World Veterinary Congress (Taipei, April, 2023), as well as travel support from the One Sustainable Health Foundation and Forum for the Geneva Health Summit (Geneva, May, 2022) and a meeting of the One Sustainable Health Foundation (Lyon, July, 2023). LFT received two grants to support One Health work in the 36 months before the submission of this Commission (German Federal Ministry of Economic Cooperation and DevelopmentOne Health Research Education and Outreach Centre in Africa and Deutsche Gesellschaft für Internationale Zusammenarbeit International Alliance against Health Risks in Wildlife Trade) and is also a Soulsby Foundation trustee. MS is affiliated with the World Organisation for Animal Health (employment period 2018–21 and contract period 2022–23). MS also received three grants for One Health work in the 36 months before the submission of this Commission (from the World Bank International Finance Corporation for animal health country projects in Vietnam and Mongolia, from the Ministry for Primary Industries, New Zealand to work with the National Animal Welfare Advisory Committee as Chair for animal health project contracts, and from the Wellcome Trust for the Research Strategy Group for the Antimicrobial Resistance Policy Accelerator project, York University, UK). MS also received travel support from the Global Strategy Lab at York University to participate in an April, 2023 workshop on Antimicrobial Resistance Global Governance in Toronto, ON, Canada and from the World Organisation for Animal Health to participate in the World Organisation for Animal Health Global Conference on Emergency Management in April, 2023. MS is on the Global Preparedness and Monitoring Board for the WHO and World Bank accountability mechanism for pandemic preparedness and response monitoring. PD received funding in the 36 months before the submission of this Commission from US Federal Agencies (National Institutes of Health, the US Agency for International Development, the Department of Defense, the Defense Threat Reduction Agency, and the National Science Foundation) to support research on emerging diseases. PD is also affiliated with the Global Virome Project, as the Secretary and Treasurer. All other authors declare no competing interests.

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The Lancet One Health Commission: harnessing our interconnectedness for equitable, sustainable, and healthy socioecological systems

Affiliations

The Lancet One Health Commission: harnessing our interconnectedness for equitable, sustainable, and healthy socioecological systems

Authors

Affiliations

Conflict of interest statement

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