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Randomized Controlled Trial
. 2025 Jul 11:2025:9309502.
doi: 10.1155/prm/9309502. eCollection 2025.

Effectiveness of Myofascial Release Combined With Capacitive-Resistive Therapy in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial

Affiliations
Randomized Controlled Trial

Effectiveness of Myofascial Release Combined With Capacitive-Resistive Therapy in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial

Peng Zhao et al. Pain Res Manag. .

Abstract

Background: Chronic nonspecific low back pain (CNLBP) is often associated with impaired mobility, functional limitations, and psychological distress. While myofascial release (MFR) and capacitive-resistive therapy (TECAR) have individually shown potential benefits, evidence regarding their combined application is limited. Methods: This assessor-blinded, three-arm randomized controlled trial included 67 patients with CNLBP. Participants were assigned to MFR alone, resistive-mode TECAR (R-TECAR) alone, or MFR plus R-TECAR. Interventions were administered twice weekly for 4 weeks, with each session lasting 20 min. Primary outcomes included the Numeric Pain Rating Scale (NPRS) and the Roland-Morris Disability Questionnaire (RMDQ), assessed at the baseline, 4 weeks, and one-and-a-half-month follow-up. Secondary outcomes encompassed thoracolumbar fascia (TLF) thickness, pressure pain threshold (PPT), trunk mobility, quality of life, anxiety, and depression. Intention-to-treat analyses were performed. Results: All interventions yielded significant improvements in pain and disability over time, although the combined MFR + R-TECAR therapy did not achieve statistically significant additional benefits compared with single therapies. Notably, a significant interaction effect emerged for PPT in the right quadratus lumborum muscle (p=0.01), with the MFR + R-TECAR group demonstrating greater improvement than R-TECAR alone. Other secondary outcomes, including TLF thickness and psychometric measures, improved over time but showed no significant between-group differences. Conclusions: Combining MFR with R-TECAR for CNLBP did not produce superior outcomes compared with individual treatments though certain muscle-specific benefits were observed. Future research should focus on optimizing treatment parameters, extending intervention and follow-up periods, and exploring individualized approaches to maximize therapeutic efficacy. Trial Registration: Chinese Registry of Clinical Trials: ChiCTR2400087961.

Keywords: TEACR therapy; chronic nonspecific low back pain; myofascial release; randomized controlled trial; thoracolumbar fascia.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
CONSORT flow diagram of the study.

References

    1. Hartvigsen J., Hancock M. J., Kongsted A., et al. What Low Back Pain Is and Why We Need to Pay Attention. The Lancet . 2018;391(10137):2356–2367. doi: 10.1016/s0140-6736(18)30480-x. - DOI - PubMed
    1. Fatoye F., Gebrye T., Odeyemi I. Real-World Incidence and Prevalence of Low Back Pain Using Routinely Collected Data. Rheumatology International . 2019;39(4):619–626. doi: 10.1007/s00296-019-04273-0. - DOI - PubMed
    1. Vos T., Lim S. S., Abbafati C., et al. Global Burden of 369 Diseases and Injuries in 204 Countries and Territories, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019. The Lancet . 2020;396(10258):1204–1222. doi: 10.1016/s0140-6736(20)30925-9. - DOI - PMC - PubMed
    1. Simons K., Rapp A., Yılmaz E., Halalmeh D. R., Moisi M. D. Innervation of the Thoracolumbar Fascia and its Relationship to Lower Back Pain. The Spine Scholar . 2018;2:19–21.
    1. Langevin H. M., Fox J. R., Koptiuch C., et al. Reduced Thoracolumbar Fascia Shear Strain in Human Chronic Low Back Pain. BMC Musculoskelet Disorder . 2011;12:p. 203. doi: 10.1186/1471-2474-12-203. - DOI - PMC - PubMed

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