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. 2025 Jul 18;13(7):e6852.
doi: 10.1097/GOX.0000000000006852. eCollection 2025 Jul.

Computed Tomography Angiography and 3-dimensional Reconstruction in Cervicofacial Burn Scar Flap Reconstruction

Qiang Ma  1 , Zhibin Yang  2 , Yun Huang  3 , Tao Guo  1 , Qiyun Luo  1 , Haidong Hu  1
Affiliations

Computed Tomography Angiography and 3-dimensional Reconstruction in Cervicofacial Burn Scar Flap Reconstruction

Qiang Ma et al. Plast Reconstr Surg Glob Open. .

Abstract

Background: This study evaluated the impact of computed tomography angiography (CTA) and 3-dimensional (3D) reconstruction on the outcomes of repairing cervicofacial burn scars using expanded extra-long fasciocutaneous flaps.

Methods: In a prospective cohort study, 64 patients were randomly assigned to an intervention group (n = 32) receiving CTA and 3D reconstruction for preoperative planning, and a control group (n = 32) without these imaging modalities. Primary outcomes included flap survival rate, postoperative complications, aesthetic outcomes, and functional restoration. In this study, we assessed inflammatory variables to evaluate postoperative inflammatory responses and oxidative stress management. We measured serum levels of interleukin-1, tumor necrosis factor-alpha, and vascular endothelial growth factor using enzyme-linked immunosorbent assay. Additionally, we evaluated oxidative stress markers, malondialdehyde and superoxide dismutase.

Results: The intervention group demonstrated a higher flap survival rate (93.75% versus 84.38%, P = 0.038), reduced postoperative complications, and improved aesthetic and functional outcomes compared with the control group. Inflammatory markers interleukin-1 and malondialdehyde were significantly lower in the intervention group (P = 0.04 and P = 0.02, respectively), suggesting better postoperative inflammatory response and oxidative stress management. The intervention group also showed a significantly lower visual analog scale score (P = 0.038), indicating better pain management.

Conclusions: The integration of CTA and 3D reconstruction in the repair of cervicofacial burn scars offers significant advantages, including improved preoperative planning, increased flap survival rates, and superior aesthetic and functional outcomes.

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Conflict of interest statement

The authors have no financial interest to declare in relation to the content of this article. This study was supported by the Ningxia Natural Science Foundation (Grant No. 2020AAC03410).

Figures

Fig. 1.
Fig. 1.
A 25-year-old female. A, CTA image. B, 3D reconstruction model.
Fig. 2.
Fig. 2.
Correction of microstomia.
Fig. 3.
Fig. 3.
A and B, Before surgery, the trapezius or deltoid skin was expanded. C, During surgery. D and E, After surgery, at 6 months.
See this image and copyright information in PMC

References

    1. Sönmez Ergün S, Yildiz K, Baygöl EG, et al. A novel approach to soft-tissue repair: reoverexpanded flaps. J Burn Care Res. 2013;34:e228–e231. - PubMed
    1. Wang C, Yang S, Pu LLQ. Pre-expanded super-thin skin perforator flaps. Clin Plast Surg. 2017;44:31–40. - PubMed
    1. Yang M, Zhao Q, Zhao Z, et al. Repair contracture deformity of perineal scar caused by burn with extra long scapular-lateral thoracic-ilioinguinal Siamese flap. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2010;24:657–660. - PubMed
    1. Tucker SC. Fasciocutaneous flaps based on a Doppler detected perforator, an illustrative series as used for burn contracture reconstruction. J Plast Reconstr Aesthet Surg. 2011;64:854–859. - PubMed
    1. Kong L, Xiong J, Ji Y, et al. Repair of cervicothoracic skin defects with extra-long transverse cervical flaps by stepwise pressure packing in children: a technical innovation. Front Pediatr. 2023;11:1269695. - PMC - PubMed

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