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Editorial
. 2025 Jun 30;14(6):3281-3285.
doi: 10.21037/tcr-2025-232. Epub 2025 Jun 25.

Advances in genomic biomarkers for lethal metastatic castration-resistant prostate cancer

Sandra A Frimpong  1 , Benjamin A Teply  2
Affiliations
Editorial

Advances in genomic biomarkers for lethal metastatic castration-resistant prostate cancer

Sandra A Frimpong et al. Transl Cancer Res. .
No abstract available

Keywords: Prostate cancer; androgen receptor signaling inhibitors (ARSIs); biomarkers; prognostic genes.

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Conflict of interest statement

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-2025-232/coif). B.A.T. has received payment for educational talks from Clinical Care Options/NCCN; served as advisory board consultant for Exelixis, Eli Lilly, and Sanofi; and is on a scientific review committee for Pfizer. The other author has no conflicts of interest to declare.

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References

    1. Chauhan PS, Alahi I, Sinha S, et al. Genomic and Epigenomic Analysis of Plasma Cell-Free DNA Identifies Stemness Features Associated with Worse Survival in Lethal Prostate Cancer. Clin Cancer Res 2025;31:151-63. 10.1158/1078-0432.CCR-24-1658 - DOI - PMC - PubMed
    1. Tsourlakis MC, Stender A, Quaas A, et al. Heterogeneity of ERG expression in prostate cancer: a large section mapping study of entire prostatectomy specimens from 125 patients. BMC Cancer 2016;16:641. 10.1186/s12885-016-2674-6 - DOI - PMC - PubMed
    1. Liu Y, Ye D, Zhang M. Epigenetic regulation of prostate cancer stem cell properties. Journal of Clinical Oncology 2016;34:524-30.
    1. Wang Z, Liao D, Li W. Androgen receptor signaling and stemness in prostate cancer: A dual perspective on growth and resistance mechanisms. Prostate Cancer and Prostatic Diseases 2018;21:211-8.
    1. Zhang X, Zhang L, Yang L. Androgen receptor-mediated stemness in prostate cancer. Journal of Cancer Research and Clinical Oncology 2019;145:1447-57.