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. 2025 Jul 4:16:1612047.
doi: 10.3389/fendo.2025.1612047. eCollection 2025.

Effectiveness of personalized continuous care in wound care of patients with diabetic foot ulcers

Yan Mi  1 , Jing Wang  1
Affiliations

Effectiveness of personalized continuous care in wound care of patients with diabetic foot ulcers

Yan Mi et al. Front Endocrinol (Lausanne). .

Abstract

Background: Diabetic foot ulcers (DFUs), a common complication of diabetes, are often accompanied by delayed wound healing, pain, psychological distress, and sleep disturbances.

Objective: To evaluate the effectiveness of personalized continuous care (PCC) compared to routine care in improving wound healing, symptom severity, and psychological/sleep outcomes in DFU patients.

Methods: A retrospective cohort study of 60 DFU patients (2021-2024) compared PCC (n=30) with routine care (n=30). Outcomes assessed included wound area reduction, granulation tissue coverage, symptom scores (ulceration, necrosis, pain), and validated psychological (SDS, SAS) and sleep (AIS) scales.

Results: The PCC group showed superior wound healing (40.51% vs. 27.43% area reduction; 61.66% vs. 46.32% granulation coverage, p<0.05), lower symptom scores (ulceration: 3.18 ± 0.45 vs. 4.46 ± 0.6; pain: 2.01 ± 0.29 vs. 3.45 ± 0.58, p<0.01), and improved psychological (SDS: 32.1 ± 3.88 vs. 44.87 ± 4.05; SAS: 30.36 ± 3.77 vs. 43.25 ± 4.56, p<0.001) and sleep outcomes (AIS: 8.23 ± 0.6 vs. 11.33 ± 0.94, p<0.001).

Conclusion: PCC enhances DFU wound healing, alleviates symptoms, and improves psychological well-being and sleep quality, supporting its integration routine clinical practice.

Keywords: diabetic foot ulcer; personalized continuous care; psychological distress; sleep quality; wound healing.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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