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. 2025 Jan 20;16(4):678-680.
doi: 10.4103/idoj.idoj_551_24. eCollection 2025 Jul-Aug.

Anetoderma as a Cutaneous Manifestation of Leprosy: A Report of Two Cases

Vijayasankar Palaniappan  1 , Tanigassalame Pavithren  1 , Saravanan Youvalakshmi  1 , Kaliaperumal Karthikeyan  1
Affiliations

Anetoderma as a Cutaneous Manifestation of Leprosy: A Report of Two Cases

Vijayasankar Palaniappan et al. Indian Dermatol Online J. .
No abstract available

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Lepromatous leprosy patient with madarosis, gynecomastia, and gynecothelia. (b) Infiltration and nodules in the earlobe. (c) Single, well-defined round to oval atrophic plaque in the posterior trunk (black arrow). (d) Flattening of anetoderma lesion upon stretching that returned to its original texture when loose (black arrow)
Figure 2
Figure 2
(a) Slit skin smear from the earlobe - Ziehl–Neelsen staining revealing multiple acid-fast bacilli with a bacteriological index (BI) of 5+. (b) Hematoxylin and Eosin stain (100×) of anetoderma lesion shows a grenz zone with flat rete ridges. (c) Hematoxylin and Eosin stain (100×) of anetoderma shows a poorly circumscribed lesion in the dermis with foamy macrophages containing lepra bacilli admixed with a few lymphocytes. (d) Verhoeff–Van Gieson stain (100×) showing a paucity of elastic fibers in the dermis
Figure 3
Figure 3
(a) Multiple well-defined erythematous nodules (black circle) over the chest and abdomen. Two, well-defined, round to oval, circumscribed atrophic plaques (black arrow) with a wrinkled appearance around the left nipple region. (b) Anetoderma lesion flattened on stretching and returned to its original texture when left loose (black arrow)
Figure 4
Figure 4
(a) Verhoeff–Van Gieson stain (40×) showing fragmentation and paucity of elastic fibers in the dermis. (b) Histopathology (Hematoxylin and Eosin stain 100×) of the erythema nodosum leprosum lesion showing mild perivascular, perineural, and peri adnexal collection of neutrophils, lymphocytes, and plasma cells in the dermis, along with a few areas with foci of necrotizing vasculitis in a collagenized stroma. (c) Dermoscopy of the anetoderma lesion showed homogenous white and yellow areas (representing elastic fiber degeneration) with distended skin markings (Image taken with Dermlite D4 189 dermoscope, 10 × magnification, polarized image)
See this image and copyright information in PMC

References

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