Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul 1;12(7):ofaf397.
doi: 10.1093/ofid/ofaf397. eCollection 2025 Jul.

Efficacy and Value of Antibiotic Allergy Evaluations in a Pediatric Solid Organ Transplant Population

Jim Liu  1 , Timothy G Chow  2 , Rory E Nicolaides  2
Affiliations

Efficacy and Value of Antibiotic Allergy Evaluations in a Pediatric Solid Organ Transplant Population

Jim Liu et al. Open Forum Infect Dis. .

Abstract

Antibiotic allergies can complicate the treatment and prophylaxis of bacterial infections in the pediatric solid organ transplant population. This single-center retrospective study revealed that antibiotic allergy evaluations and testing could safely and effectively be performed in this population group, with a positive economic value associated with sulfonamide allergy delabeling.

Keywords: allergy; antibiotic allergy delabeling; pediatric; solid organ; transplant.

PubMed Disclaimer

Conflict of interest statement

Potential conflicts of interest. T.G.C. receives grant support from the National Institutes of Health (grant U01 AI184071). T.G.C. reports personal fees from Sarepta Therapeutics outside the submitted work.

Figures

Graphical Abstract
Graphical Abstract
See this image and copyright information in PMC

References

    1. Magee JC, Krishnan SM, Benfield MR, Hsu DT, Shneider BL. Pediatric transplantation in the United States, 1997–2006. Am J Transplant 2008; 8(4p2):935–45. - PubMed
    1. Mónica F-A, Michaels MG. Infections in pediatric solid organ transplant recipients. Semin Pediatr Surg 2006; 15:153–61. - PMC - PubMed
    1. Horslen S, Barr ML, Christensen LL, Ettenger R, Magee JC. Pediatric transplantation in the United States, 1996–2005. Am J Transplant 2007; 7(5 Pt 2):1339–58. - PubMed
    1. van Delden C, Stampf S, Hirsch HH, et al. Burden and timeline of infectious diseases in the first year after solid organ transplantation in the Swiss Transplant Cohort Study. Clin Infect Dis 2020; 71:e159–69. - PMC - PubMed
    1. Star K, Norén GN, Nordin K, Edwards IR. Suspected adverse drug reactions reported for children worldwide: an exploratory study using VigiBase. Drug Saf 2011; 34:415–28. - PubMed