Defining research priorities in sepsis: from protocols to personalisation

Stephen J Aston^{1

2}, Stacy Todd², Neil French^{2

3}

Affiliations

¹ Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
² Tropical and Infectious Diseases Unit, Royal Liverpool Hospital, University Hospitals of Liverpool Group, Liverpool, UK.
³ Institute of Infection, Veterinary and Ecological Science, University of Liverpool, Liverpool, UK.

Editorial

Stephen J Aston et al. Anaesthesia. 2025 Oct.

. 2025 Oct;80(10):1182-1185.

doi: 10.1111/anae.16693. Epub 2025 Jul 21.

Stephen J Aston^{1

2}, Stacy Todd², Neil French^{2

3}

¹ Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
² Tropical and Infectious Diseases Unit, Royal Liverpool Hospital, University Hospitals of Liverpool Group, Liverpool, UK.
³ Institute of Infection, Veterinary and Ecological Science, University of Liverpool, Liverpool, UK.

No abstract available

Keywords: outcomes; research priorities; sepsis.

References

1. Bion J, Barton G, Boyle A. Statement on the initial antimicrobial treatment of sepsis: V2.0. 2022. https://www.aomrc.org.uk/wp‐content/uploads/2022/10/Statement_on_the_ini....
1. Hex N, Retzler J, Bartlett C, Arber M. The cost of sepsis care in the UK. York: York Health Economics Consortium, 2017. https://sepsistrust.org/wp‐content/uploads/2024/11/YHEC‐Sepsis‐Report‐17....
1. McPeake J, Ahmad N, Bradely K, et al. Top 10 research priorities for sepsis research determined by patient, carers, and clinicians. Anaesthesia 2025; 80: 1190–1198. https://doi.org/10.1111/anae.16634.
1. De Backer D, Deutschman CS, Hellman J, et al. Surviving sepsis campaign research priorities 2023. Crit Care Med 2024; 52: 268–296. https://doi.org/10.1097/CCM.0000000000006135.
1. Van Der Poll T, Shankar‐Hari M, Wiersinga WJ. The immunology of sepsis. Immunity 2021; 54: 2450–2464. https://doi.org/10.1016/j.immuni.2021.10.012.