An ancient immune pathway enables animal metamorphosis

Elizabeth Heath-Heckman^{1

2}

Affiliations

¹ Department of Microbiology, Genetics, and Immunology, Michigan State University, East Lansing, MI 48824.
² Department of Integrative Biology, Michigan State University, East Lansing, MI 48824.

Comment

Elizabeth Heath-Heckman. Proc Natl Acad Sci U S A. 2025.

. 2025 Jul 29;122(30):e2512734122.

doi: 10.1073/pnas.2512734122. Epub 2025 Jul 21.

Elizabeth Heath-Heckman^{1

2}

¹ Department of Microbiology, Genetics, and Immunology, Michigan State University, East Lansing, MI 48824.
² Department of Integrative Biology, Michigan State University, East Lansing, MI 48824.

No abstract available

Conflict of interest statement

Competing interests statement:The author declares no competing interest.

MyD88 knockdown by RNAi prevents bacterial stimulation of tubeworm metamorphosis.
Darin E, Farrell MV, Ali TN, Rivera Alfaro J, Malter KE, Shikuma NJ. Darin E, et al. Proc Natl Acad Sci U S A. 2025 Jun 10;122(23):e2505805122. doi: 10.1073/pnas.2505805122. Epub 2025 Jun 2. Proc Natl Acad Sci U S A. 2025. PMID: 40455987 Free PMC article.

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