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. 2025 Jul 22;80(Supplement_1):S66-S77.
doi: 10.1093/cid/ciaf054.

Importance of Targeted Communication Strategies During COVID-19 Vaccination Campaigns in Mozambique: Results of a Mixed-Methods Acceptability Study

Caroline De Schacht  1 , Igor Ubisse Capitine  2 , Carlota Lucas  1 , Ana Muteerwa  3 , Paula Paulo  1 , Alvaro Manhiça  2 , Fernando Padama  4 , Celso Belo  1 , Leonildo Nhampossa  5 , Graça Matsinhe  5 , Zhihong Yu  6 , C William Wester  7   8
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Importance of Targeted Communication Strategies During COVID-19 Vaccination Campaigns in Mozambique: Results of a Mixed-Methods Acceptability Study

Caroline De Schacht et al. Clin Infect Dis. .

Abstract

Background: Mozambique implemented a phased roll-out of COVID-19 vaccination in 2021. This study aimed to evaluate COVID-19 vaccine acceptability among higher-risk populations in Zambézia Province.

Methods: A mixed-methods study in Zambézia Province assessed knowledge, perceptions, and acceptability of COVID-19 vaccination. Structured questionnaire-based surveys among community health workers/volunteers, taxi drivers, and persons with HIV; and focus group discussions using semi-structured guides with community/religious leaders, adults aged 18-49 years and adults aged 50+ years were conducted in August-September 2021. Surveys were captured using tablets; group discussions were recorded. Univariate analyses were performed for quantitative data; qualitative data were analyzed thematically.

Results: A total of 731 individuals participated (539 survey respondents; 192 discussion respondents); 53% male (n = 386) and 74% urban (n = 544) residents. Most had heard about COVID-19 vaccines, mainly through television and/or radio. Trustworthy information sources mentioned were community leaders and healthcare providers. Among survey respondents, 249/539 (46%) reported having received at least 1 vaccine dose. Motivators for vaccination mentioned by survey respondents were "belief that vaccines protect themselves" (72%), "belief it would protect their family" (17%). Myths and beliefs, misinformation, and long queues were main barriers for vaccination mentioned in group discussions. Participants suggested that campaigns should focus on communication talks led by health professionals, in partnership with community or church leaders and/or community health workers/volunteers.

Conclusions: This study showed that information on COVID-19 vaccination had successfully reached the vast majority of study participants, mainly via radio and television. Targeted campaigns specific for rural and urban contexts can increase awareness and uptake of vaccination.

Keywords: COVID-19 vaccination; Mozambique; acceptability; communication strategies.

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Conflict of interest statement

Potential conflicts of interest. The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

Figures

Figure 1.
Figure 1.
Study locations in the 2 selected districts (marked with red dots). Figure by C-Saúde.
Figure 2.
Figure 2.
Acceptance of at least 1 dose of COVID-19 vaccination by sex, area, target group, and age group. Bivariate tests were performed using chi-square test. Abbreviations: CHW, community health workers; COVID-19, coronavirus disease 2019; PWH, persons with human immunodeficiency virus.
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