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. 2025 Jul 22;21(7):e1013346.
doi: 10.1371/journal.ppat.1013346. eCollection 2025 Jul.

Through thick and thin: The vaginal microbiome as both occupant and healer

Affiliations

Through thick and thin: The vaginal microbiome as both occupant and healer

Mart Sillen et al. PLoS Pathog. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Multifactorial influences on the vaginal microbiome.
This figure illustrates the intrinsic, hormonal, behavioral, and background factors that shape the structure and function of the vaginal microbiome. Host genetics and immune responses, hormonal fluctuations, personal habits (e.g., hygiene, sexual activity, diet, smoking, parity), and biogeographical context all influence microbial composition and resilience. These factors act in concert, modulating susceptibility to dysbiosis and shaping individual trajectories of vaginal health. Figure created with BioRender.com [,,–21].

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