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Editorial
. 2025 Jul 15;16(7):108209.
doi: 10.4239/wjd.v16.i7.108209.

Systemic immune indicators: Early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus

Affiliations
Editorial

Systemic immune indicators: Early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus

Basavraj S Nagoba et al. World J Diabetes. .

Abstract

This editorial delves into the potential of systemic immune indicators (SIIs) as early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus. By exploring the recent study published by Cao et al, this article aims to highlight the importance of early detection and intervention. This study comprehensively analyzes various SIIs, examining their correlation with renal complications in newly diagnosed type 1 diabetic children. The findings reveal a significant association between immune system dysregulation and the onset of renal damage, suggesting that certain immune indicators can be early markers for predicting renal complications. This editorial emphasizes the clinical implications and applications of utilizing SIIs for early detection in pediatric diabetes care. It underscores the importance of innovative diagnostic approaches and illustrates real-world applications and outcomes. Additionally, it addresses the challenges and considerations in adopting these indicators and outlines future research directions to enhance diabetes management in children.

Keywords: Early predictors; Pediatric care; Renal damage; Systemic immune indicators; Type 1 diabetes.

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Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Figures

Figure 1
Figure 1
A conceptual visual schematic. EHR: Electronic health record.

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