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Review
. 2025 Jul 18:17:2165-2174.
doi: 10.2147/IJWH.S522708. eCollection 2025.

Characteristics of Gut Microbiota in Patients with Polycystic Ovary Syndrome and Its Association with Metabolic Abnormalities: A Review

Shuang Liu  1 , Linqi Cheng  2 , Sen Li  3
Affiliations
Review

Characteristics of Gut Microbiota in Patients with Polycystic Ovary Syndrome and Its Association with Metabolic Abnormalities: A Review

Shuang Liu et al. Int J Womens Health. .

Abstract

Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder that has garnered attention in recent years for its intricate relationship with gut microbiota, which plays a significant role in the metabolic abnormalities associated with this condition. This review focuses on the characteristics of gut microbiota in polycystic ovary syndrome (PCOS). By analyzing current literature, we will focus on the alterations in gut microbiota composition, influential factors, and the pathophysiological mechanisms linking gut microbiota and PCOS, diagnostic approaches, therapeutic strategies, as well as controversies and future directions in this field are discussed. Understanding these relationships may provide insights into the disease mechanism and highlight novel treatment strategies for managing PCOS.

Keywords: endocrine disorders; gut microbiota; metabolic abnormalities; microbiome; polycystic ovary syndrome.

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Conflict of interest statement

All authors report no relevant conflicts of interest in this work.

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