Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul 23.
doi: 10.1111/1346-8138.17859. Online ahead of print.

Japanese Dermatological Association's Clinical Practice Guidelines for Alopecia Areata 2024: A Complete English Translated Version

Affiliations

Japanese Dermatological Association's Clinical Practice Guidelines for Alopecia Areata 2024: A Complete English Translated Version

Manabu Ohyama et al. J Dermatol. .

Abstract

This is an English-translated version of the Japanese Dermatological Association's clinical practice guidelines for alopecia areata (AA) 2024. It includes the sections of summary, pathogenesis and epidemiology, evaluation and diagnosis, and treatment of AA. Updates based on recent evidence/advances were made in each part. The treatment part contains the statements of recommendation for 25 clinical questions (CQs) with respective recommendation/evidence levels. AA-cube, a graphic illustration conceptualizing the treatment strategy based on individual patients' factors, was newly proposed. Taking into account the recent approval of a JAK inhibitor and a JAK3/TEC family kinase selective inhibitor, a CQ for these modalities was also added. These guidelines aim to support evidence-based management of AA as well as prompt understanding of disease etiopathogenesis.

PubMed Disclaimer

References

    1. R. C. Betz, L. Petukhova, S. Ripke, et al., “Genome‐Wide Meta‐Analysis in Alopecia Areata Resolves HLA Associations and Reveals Two New Susceptibility Loci,” Nature Communications 6 (2015): 5966.
    1. L. Petukhova, M. Duvic, M. Hordinsky, et al., “Genome‐Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity,” Nature 466 (2010): 113–117.
    1. D. Ahn, H. Kim, B. Lee, and D. H. Hahm, “Psychological Stress‐Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways,” International Journal of Molecular Sciences 24 (2023): 11711.
    1. R. Kageyama, T. Ito, S. Nakazawa, T. Shimauchi, T. Fujiyama, and T. Honda, “A Case of Telogen Effluvium Followed by Alopecia Areata After SARS‐CoV‐2 Infection,” Journal of Dermatology 50 (2023): e32–e34.
    1. B. Nguyen and A. Tosti, “Alopecia Areata After COVID‐19 Infection and Vaccination: A Cross‐Sectional Analysis,” Journal of the European Academy of Dermatology and Venereology 37 (2023): e7–e8.