Editorial for the Special Issue "Aging, Age-Related Changes in the Brain and the Progression of Alzheimer's Disease"
- PMID: 40699717
- PMCID: PMC12109851
- DOI: 10.3390/cimb47050318
Editorial for the Special Issue "Aging, Age-Related Changes in the Brain and the Progression of Alzheimer's Disease"
Abstract
Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline, memory impairment, and synaptic dysfunction [...].
Conflict of interest statement
The author declares no conflicts of interest.
Similar articles
-
Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer's Disease and MCI: A Review.Int J Mol Sci. 2023 Jan 14;24(2):1659. doi: 10.3390/ijms24021659. Int J Mol Sci. 2023. PMID: 36675177 Free PMC article.
-
Age-Associated Cortical Thinning in Speech Motor Regions Precedes Hippocampal Decline: Implications for Alzheimer's Disease.Hum Brain Mapp. 2025 Aug 1;46(11):e70288. doi: 10.1002/hbm.70288. Hum Brain Mapp. 2025. PMID: 40698900 Free PMC article.
-
Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model.Elife. 2024 Jan 29;12:RP89453. doi: 10.7554/eLife.89453. Elife. 2024. PMID: 38285009 Free PMC article.
-
Predicting cognitive decline: Deep-learning reveals subtle brain changes in pre-MCI stage.J Prev Alzheimers Dis. 2025 May;12(5):100079. doi: 10.1016/j.tjpad.2025.100079. Epub 2025 Feb 6. J Prev Alzheimers Dis. 2025. PMID: 39920001 Free PMC article.
-
18F PET with florbetapir for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).Cochrane Database Syst Rev. 2017 Nov 22;11(11):CD012216. doi: 10.1002/14651858.CD012216.pub2. Cochrane Database Syst Rev. 2017. PMID: 29164603 Free PMC article.
References
-
- Zernov N., Veselovsky A.V., Poroikov V.V., Melentieva D., Bolshakova A., Popugaeva E. New Positive TRPC6 Modulator Penetrates Blood-Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice. Int. J. Mol. Sci. 2022;23:13552. doi: 10.3390/ijms232113552. - DOI - PMC - PubMed
-
- Basak J.M., Ferreiro A., Cohen L.S., Sheehan P.W., Nadarajah C.J., Kanan M.F., Sukhum K.V., Dantas G., Musiek E.S. Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer’s disease. Neurobiol. Dis. 2021;152:105292. doi: 10.1016/j.nbd.2021.105292. - DOI - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources