Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Aug;39(8):e70252.
doi: 10.1111/ctr.70252.

Cultural Influences, Considerations, and Challenges for Organ Donation and Liver Transplantation Around the World

Affiliations
Review

Cultural Influences, Considerations, and Challenges for Organ Donation and Liver Transplantation Around the World

Sher-Lu Pai et al. Clin Transplant. 2025 Aug.

Abstract

Introduction: Although liver transplantation (LT) rates have increased globally, the demand for organs still exceeds the supply. This review highlights cultures with significant influences on organ donation and LT.

Methods: We performed a literature search for articles related to cultures, ethnologies, philosophies, policies, religions, socio-economic factors, and other influences affecting organ donation in LT around the world.

Results: There are astonishing similarities between different cultures. In Africa, Asia, and Europe, people often view the postmortem bodies as sacred and believe that their bodies are gifts from "God" or ancestors. To respect the gift of life, to have a chance in reincarnation, or to enjoy life after death, many believe that their bodily sanctity must be preserved. In Asia, Europe, and Latin America, there is a general reluctance to speak about death. Religions also play an important role in people's views on organ donation. Different regions around the world have similar challenges to organ donation, such as misconceptions about organ trafficking, political and economic instability, and a lack of governmental or religious support.

Conclusion: Addressing the complexities of organ donation and LT requires a multifaceted approach. Culturally sensitive education tailored to diverse communities can dispel myths and misconceptions surrounding organ donation. Fostering partnerships between healthcare providers, religious leaders, community organizations, and policymakers can further facilitate open dialogues and promote organ donation as a noble act to save lives.

Social media: Similar cultures around the world post challenges for organ donation. Organizations should foster partnerships between healthcare providers, politicians, and religious leaders to promote donation.

Keywords: economic stability; liver transplantation; organ trafficking; policy; religion; tissue and organ procurement.

PubMed Disclaimer

References

    1. Global Observatory on Donation and Transplantation. Organ Donation and Transplantation Activities. 2012, accessed May 22, 2024, https://www.transplant‐observatory.org/download/2012‐activity‐data/.
    1. Global Observatory on Donation and Transplantation. Global Data. 2024, accessed April 7, 2025, https://www.transplant‐observatory.org/data‐charts‐and‐tables/.
    1. K. W. Bowman and S. A. Richard, “Culture, Brain Death, and Transplantation,” Progress in Transplantation 13, no. 3 (2003): 211–215, https://doi.org/10.1177/152692480301300308.
    1. S. Streit, C. Johnston‐Webber, J. Mah, et al., “Ten Lessons from the Spanish Model of Organ Donation and Transplantation,” Transplant International 36 (2023): 11009, https://doi.org/10.3389/ti.2023.11009.
    1. N. Zeitel‐Bank and A. Pickel. The Spanish Organ Donation & Transplantation Model as a Role Model for Austria and Germany? 2015, accessed April 23, 2025, http://ffhoarep.fh‐ooe.at/bitstream/123456789/405/1/FFH2015‐GW2‐1.pdf.

LinkOut - more resources