Solitary fibrous tumor of the nasal septum: a case report and literature review

Abstract

Solitary fibrous tumors (SFT) are rare spindle cell neoplasms of mesenchymal origin, typically occurring in the pleura, with extra-pleural manifestations being uncommon. SFTs of the nasal cavity are particularly rare, with limited cases documented in the literature. This report presents the case of a 62-year-old female with a solitary fibrous tumor arising from the nasal septum. The patient presented with a unilateral nasal mass, obstruction, and nasal discharge, which did not improve with antibiotics. The tumor was successfully excised via an endonasal endoscopic approach, and histopathological analysis confirmed the diagnosis of an SFT with positive CD34 and CD99 markers. The patient remained symptom-free with no recurrence over 2 years of follow-up. This case highlights the importance of considering SFTs in the differential diagnosis of nasal masses and underscores the effectiveness of endonasal endoscopic resection as a minimally invasive treatment approach.

Keywords: endoscopic sinus surgery; nasal tumors; solitary fibrous tumors; spindle cell neoplasm.

Figure 1

(A) Nasal endoscopic examination showing left nasal septal mass. (B) Computed tomography scan of the paranasal sinuses showing a focal soft tissue lesion arising from the left deviated nasal septum, causing thinning of the left nasal bone measuring 2.2 × 1.7 × 2.7 cm.

Figure 2

Nasal septal mass post endoscopic excision.