Preexisting Depression and Prostate Cancer Survival

Lei Zhang¹, Xian-Zhang Hu^{1

2}, Xiao Xia Li^{1

2}, Gyorgy Petrovics^{2

3}, Anwar E Ahmed⁴, David M Benedek¹, Robert J Ursano¹

Affiliations

¹ Center for the Study of Traumatic Stress, Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
² Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland.
³ Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
⁴ Department of Preventive Medicine and Biostatistics, School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

Free article

Lei Zhang et al. JAMA Netw Open. 2025.

Free article

. 2025 Jul 1;8(7):e2523143.

doi: 10.1001/jamanetworkopen.2025.23143.

Lei Zhang¹, Xian-Zhang Hu^{1

2}, Xiao Xia Li^{1

2}, Gyorgy Petrovics^{2

3}, Anwar E Ahmed⁴, David M Benedek¹, Robert J Ursano¹

¹ Center for the Study of Traumatic Stress, Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
² Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland.
³ Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
⁴ Department of Preventive Medicine and Biostatistics, School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

No abstract available

Plain language summary

This cohort study evaluates whether there are survival differences between patients with prostate cancer with vs without preexisting depression.