The Secret Life of a Lost Guidewire
- PMID: 40713126
- PMCID: PMC12441537
- DOI: 10.1016/j.jaccas.2025.104181
The Secret Life of a Lost Guidewire
Abstract
Background: Lost guidewires during central venous catheterization are rare but serious, requiring prompt removal to reduce morbidity and mortality.
Case summary: A 58-year-old woman presented with a pulsating back mass and a spontaneous bruise under her left clavicle. More than 10 years ago, a 0.035-inch guidewire had been lost in her circulation, and retrieval attempts had failed. Computed tomography scan revealed a fragmented guidewire that had crossed into the arterial circulation through a patent foramen ovale and extended through the anterior mediastinum. After a discussion among the heart team, the decision was made to remove the wire percutaneously.
Discussion: This case highlights the risks of guidewire loss and the successful use of advanced catheter techniques for complex wire retrieval.
Take-home messages: Iatrogenic guidewire loss is associated with significant risk of morbidity and mortality, and the guidewire must be removed. A fragmented wire can be removed percutaneously by forming a free loop with an additional wire. If wire embolization is recognized during central venous catheter insertion, several bedside techniques can be attempted to rapidly correct the complication.
Keywords: CT; complication; guidewire; patent foramen ovale.
Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Funding Support and Author Disclosures Dr Samuel McGrath is undergoing a Clinical Research Training Fellowship (CRTF) funded by the British Heart Foundation (FS/CRTF/22/24187). Prof Hildick-Smith is a Proctor/Advisory to Abbott, Boston, Medtronic, and Edwards.
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