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. 2025 Jun 25;15(7):1005.
doi: 10.3390/life15071005.

Optimal Low-Frequency Parameter of Percutaneous Electrical Nerve Stimulation in Patients with Lower Back Pain: A Pilot Study

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Optimal Low-Frequency Parameter of Percutaneous Electrical Nerve Stimulation in Patients with Lower Back Pain: A Pilot Study

Roberto San-Emeterio-Iglesias et al. Life (Basel). .

Abstract

Background: The methodology of ultrasound (US)-guided percutaneous neuromodulation (PNM) remains unclear. Objective: To determine the optimal stimulation frequency (3 Hz vs. 10 Hz) during the short-term application of US-guided PNM on the sciatic nerve, we assessed the therapeutic benefits, including pain reduction, hip passive internal rotation range of motion (IR-ROM), balance, and functionality, in patients with chronic low back pain (LBP). Methods: Forty patients with LBP were randomly assigned to two groups, each receiving isolated percutaneous electrical stimulation of the sciatic nerve. One group received stimulation at 3 Hz, while the other received stimulation at 10 Hz. Pain intensity, hip passive IR-ROM, hip muscle strength, and the Oswestry Disability Index (ODI) were measured before and one week after the intervention. Results: Both interventions significantly reduced pain and improved ROM, balance, and functionality after one week (p = 0.001). However, significant between-group (treatment × time) differences were observed for pain intensity (p = 0.001) and flexion strength in the non-intervention limb (p = 0.01), though the effect size was small (η2 = 0.1). Conclusions: US-guided PNM applied to the sciatic nerve was more effective at 3 Hz than at 10 Hz in relieving pain intensity in patients with LBP.

Keywords: low back; low-frequency parameters; nerve stimulation; pain.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
CONSORT flow diagram of subject recruitment for the study.
Figure 2
Figure 2
Ultrasound-guided percutaneous neuromodulation. (A) Proximal location on the sciatic nerve; (B) ultrasound image of the sciatic nerve; (C) electrical stimulation to the sciatic nerve using a needle. Abbreviations: GM, gluteus maximus; SN, the sciatic nerve.

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