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Review
. 2025 Jul 12;14(14):4942.
doi: 10.3390/jcm14144942.

Use of Artificial Intelligence Methods for Improved Diagnosis of Urinary Tract Infections and Urinary Stone Disease

Theodor Florin Pantilimonescu  1 , Costin Damian  2 , Viorel Dragos Radu  3 , Maximilian Hogea  4 , Oana Andreea Costachescu  4 , Pavel Onofrei  5 , Bogdan Toma  6 , Denisa Zelinschi  6 , Iulia Cristina Roca  7 , Ramona Gabriela Ursu  2 , Luminita Smaranda Iancu  2 , Ionela Lacramioara Serban  1
Affiliations
Review

Use of Artificial Intelligence Methods for Improved Diagnosis of Urinary Tract Infections and Urinary Stone Disease

Theodor Florin Pantilimonescu et al. J Clin Med. .

Abstract

Urinary tract infections (UTIs) are a common pathology worldwide, frequently associated with kidney stones. We aimed to determine how artificial intelligence (AI) could assist and enhance human medical activities in this field. We performed a search in PubMed using different sets of keywords. When using the keywords "AI, artificial intelligence, urinary tract infections, Escherichia coli (E. coli)", we identified 16 papers, 12 of which fulfilled our research criteria. When using the keywords "urolithiasis, AI, artificial intelligence", we identified 72 results, 30 of which were suitable for analysis. We identified that AI/machine learning can be used to detect Gram-negative bacilli involved in UTIs in a fast and accurate way and to detect antibiotic-resistant genes in E. coli. The most frequent AI applications for urolithiasis can be summarized into three categories: The first category relates to patient follow-up, trying to improve physical and medical conditions after specific urologic surgical procedures. The second refers to urinary stone disease (USD), focused on stone evaluation, using different AI and machine learning systems, regarding the stone's composition in terms of uric acid, its dimensions, its volume, and its speed of detection. The third category comprises the comparison of the ChatGPT-4, Bing AI, Grok, Claude, and Perplexity chatbots in different applications for urolithiasis. ChatGPT-4 has received the most positive evaluations. In conclusion, the impressive number of papers published on different applications of AI in UTIs and urology suggest that machine learning will be exploited effectively in the near future to optimize patient follow-up, diagnosis, and treatment.

Keywords: Artificial Intelligence; UTIs; Urolithiasis; diagnostic advancements; urinary infection management.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
The benefits of using AI for the improved diagnosis of UTIs.
Figure 2
Figure 2
The benefits of using AI for USD.
See this image and copyright information in PMC

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