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. 2025 Jul 21;14(14):5165.
doi: 10.3390/jcm14145165.

Cross-Sectional and Quasi-Longitudinal Examination of Childhood and Adult Cognitive Disengagement Syndrome, Depression, Anxiety, Stress, and Insomnia

Affiliations

Cross-Sectional and Quasi-Longitudinal Examination of Childhood and Adult Cognitive Disengagement Syndrome, Depression, Anxiety, Stress, and Insomnia

Dena Sadeghi-Bahmani et al. J Clin Med. .

Abstract

Background: Longitudinal studies on cognitive disengagement syndrome (CDS) are scarce, and only one study has investigated the trajectory of CDS from childhood to early adulthood. Given this, the aims of the present study were to explore, with a quasi-longitudinal design, (1) whether scores for childhood CDS were associated with scores for CDS during early adulthood; (2) whether childhood CDS scores were associated with childhood and adult scores for depression, anxiety, stress, and insomnia; (3) whether childhood CDS, depression, anxiety, stress, and insomnia and adult depression, anxiety, stress, and insomnia were independently associated with adult scores for CDS, and (4) whether childhood CDS scores were directly and indirectly associated with adult CDS scores via adult depression and stress in two conditional effect models. Methods: A total of 246 young adult students (mean age = 22.62; 56.3% females) participated in a cross-sectional and quasi-longitudinal study. The participants completed questionnaires assessing CDS (Adult Concentration Inventory; ACI), depression, anxiety, stress, and insomnia for the following two developmental periods: for the present time point as young adults and for a past time point, when they were about eight years old. To enable retrospective past recall, the participants undertook a standardized imagination exercise. Results: Childhood scores for CDS, depression, anxiety, stress, and insomnia were highly associated with adult scores for CDS, depression, anxiety, stress, and insomnia. In the regression model, higher childhood scores for CDS, depression, and anxiety and higher adult scores for depression, stress, and insomnia, but not adult anxiety, were strongly and independently associated with adult scores for CDS. In the two conditional effects models, childhood CDS was associated with adult CDS directly and indirectly via adult depression and adult stress. Conclusions: In this quasi-longitudinal study, childhood scores for CDS were associated with adult scores for CDS, suggesting a potentially stable trajectory of CDS from childhood to early adulthood. Further, the two conditional effects models suggested that childhood and adult CDS were both directly and indirectly associated via adult depression and stress. As such, symptoms of depression, anxiety, stress, and insomnia should be considered in conceptualizations of adult CDS. Next, given that standardized psychotherapeutic interventions for depression, stress, and insomnia are available, such interventions might also favorably impact CDS symptoms. These findings further underscore the importance of prospective longitudinal and intervention studies on adult CDS.

Keywords: adulthood; anxiety; childhood; cognitive disengagement syndrome; conditional effect models; depression; insomnia; quasi-longitudinal study; sluggish cognitive tempo; stress.

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Conflict of interest statement

The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Figures

Figure 1
Figure 1
Model 1 Direct associations between childhood CDS and adulthood CDS, and indirect associations between childhood CDS and adulthood CDS via adulthood depression.
Figure 2
Figure 2
Model 2 Direct associations between childhood CDS and adulthood CDS, and indirect associations between childhood CDS and adulthood CDS via adult stress.

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References

    1. Becker S.P., Willcutt E.G., Leopold D.R., Fredrick J.W., Smith Z.R., Jacobson L.A., Burns G.L., Mayes S.D., Waschbusch D.A., Froehlich T.E., et al. Report of a Work Group on Sluggish Cognitive Tempo: Key Research Directions and a Consensus Change in Terminology to Cognitive Disengagement Syndrome. J. Am. Acad. Child Adolesc. Psychiatry. 2023;62:629–645. doi: 10.1016/j.jaac.2022.07.821. - DOI - PMC - PubMed
    1. Becker S.P. Cognitive disengagement syndrome: A construct at the crossroads. Am. Psychol. 2025 doi: 10.1037/amp0001517. - DOI - PMC - PubMed
    1. Barkley R.A. Distinguishing sluggish cognitive tempo from attention-deficit/hyperactivity disorder in adults. J. Abnorm. Psychol. 2012;121:978–990. doi: 10.1037/a0023961. - DOI - PubMed
    1. Mayes S.D., Becker S.P., Calhoun S.L., Waschbusch D.A. Comparison of the Cognitive Disengagement and Hypoactivity Components of Sluggish Cognitive Tempo in Autism, ADHD, and Population-Based Samples of Children. Res. Child. Adolesc. Psychopathol. 2023;51:47–54. doi: 10.1007/s10802-022-00969-3. - DOI - PubMed
    1. Mayes S.D., Becker S.P., Waschbusch D.A. Cognitive Disengagement Syndrome and Autism Traits are Empirically Distinct from each Other and from Other Psychopathology Dimensions. Res. Child. Adolesc. Psychopathol. 2025;53:151–161. doi: 10.1007/s10802-024-01281-y. - DOI - PubMed

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