Surgical Treatment of Lung Cancer in Situs Inversus Totalis-A Case Report

Abstract

Situs inversus totalis (SIT) is a congenital anomaly that involves the mirror rearrangement of the thoracic and abdominal internal organs. In this paper, we report a 56-year-old male patient with previously confirmed SIT, who was admitted to the hospital for the diagnosis and surgical treatment of non-small-cell lung cancer, located in the sixth right pulmonary segment. The patient underwent segmentectomy with mediastinal and hilar lymphadenectomy. Furthermore, we screened the PubMed and Embase databases for reports of the surgical treatment of patients with SIT and lung cancer. Articles describing inoperable and disseminated disease, as well as patients qualified for palliative treatment, were not included. Ultimately, we compared 21 articles (including the one described here). Data about the clinical condition, tumor characteristics, treatment, and histopathological examination were extracted and summarized.

Keywords: lung cancer; situs inversus totalis; thoracic surgery.

Figure 1

(A,B) Pre- and postoperative chest X-rays of the patient with SIT and lung cancer. (C,D) Chest CT showing rearrangement of mediastinal vessels and 2.5 cm tumor in VI right segment with enlargement of lymph nodes 4R and 7. (E,F) Abdominal CT showing position of the liver on the left side and position of the aorta on the right side.