[Autoimmune diseases and immunotherapies]

Abstract

Immune checkpoint inhibitors are now an essential therapy for lung cancer. These monoclonal antibodies are nevertheless responsible for immune-related adverse events. With particular regards for patients with previous autoimmune disease, less is known about the efficacy and safety of immune checkpoint inhibitors, but also about the consequences of steroids or other specific therapies. The aim of this article is to synthesize available data in the literature on immune checkpoint inhibitors experience in patients with both lung cancer and autoimmune disease.

Keywords: Auto-immunité; Autoimmunity; Cancer bronchique; Immunotherapy; Immunothérapie; Lung cancer; Poussée; Thrust; Tolerance; Tolérance.