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. 2025 Dec;19(6):1497-1498.
doi: 10.1007/s12072-025-10885-5. Epub 2025 Jul 29.

Response to Letter to Editor: "Systemic inflammation and prognosis in HCC: a closer look"

Alba Rocco  1 , Costantino Sgamato  2 , Vittorio Simeon  3 , Debora Compare  2 , Gerardo Nardone  2 ; ITA.LI.CA group
Affiliations

Response to Letter to Editor: "Systemic inflammation and prognosis in HCC: a closer look"

Alba Rocco et al. Hepatol Int. 2025 Dec.
No abstract available

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Conflict of interest statement

Declarations. Conflict of interest: None of the authors declared a conflict of interest. Ethical approval: The ITA.LI.CA database management conforms to the past and current Italian legislation regarding privacy, and the present study conforms to the ethical guidelines of the Declaration of Helsinki. The study was approved by the Institutional Review Board of the ITA.LI.CA coordinating center, Alma Mater Studiorum University of Bologna, on 15th May 2012 (approval number 99/2012/O/Oss). Informed consent: Written informed consent was obtained from all participants.

References

    1. Rocco A, Sgamato C, Pelizzaro F, et al. Systemic inflammatory response markers improve the discrimination for prognostic model in hepatocellular carcinoma. Hepatol Int. 2025. https://doi.org/10.1007/s12072-025-10806-6 - DOI - PubMed
    1. Vitale A, Svegliati-Baroni G, Ortolani A, et al. Epidemiological trends and trajectories of MAFLD-associated hepatocellular carcinoma 2002–2033: the ITA.LI.CA database. Gut. 2023;72(1):141–152 - DOI - PubMed
    1. Halazun KJ, Hardy MA, Rana AA, et al. Negative impact of neutrophil-lymphocyte ratio on outcome after liver transplantation for hepatocellular carcinoma. Ann Surg. 2009;250(1):141–151 - DOI - PubMed
    1. Lin WF, Zhong MF, Zhang YR, et al. Prognostic role of platelet-to-lymphocyte ratio in hepatocellular carcinoma with different BCLC stages: a systematic review and meta-analysis. Gastroenterol Res Pract. 2018;2018:1–10 - DOI

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