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. 2025 Jul 30.
doi: 10.1097/CRD.0000000000001019. Online ahead of print.

Malignant Pericardial Disease

Affiliations

Malignant Pericardial Disease

Omar A Seyam et al. Cardiol Rev. .

Abstract

Pericardial involvement in cancer can present with various clinical manifestations, including constrictive pericarditis, pericardial tamponade, or chronic pericardial effusions. Since the incidence of malignant pericardial illness is more widespread than is generally understood, a strong index of suspicion is required to identify its many characteristics. Therefore, in this article, we review the etiology, mechanism, clinical presentation, and their management.

Keywords: constrictive pericarditis; malignant pericardial disease; pericardial effusion.

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Conflict of interest statement

Disclosure: The authors declare no conflict of interest.

References

    1. Chiles C, Woodard PK, Gutierrez FR, et al. Metastatic involvement of the heart and pericardium: CT and MR imaging. Radiographics. 2001;21:439–449.
    1. Abbara S, Kalva SP. Problem Solving in Cardiovascular Imaging: Expert Consult-Online and Print. Elsevier Health Sciences; 2012.
    1. Maggiolini S, De Carlini CC, Ferri LA, et al. The role of early contrast-enhanced chest computed tomography in the aetiological diagnosis of patients presenting with cardiac tamponade or large pericardial effusion. Eur Heart J Cardiovasc Imaging. 2016;17:421–428.
    1. Lestuzzi C, Bearz A, Lafaras C, et al. Neoplastic pericardial disease in lung cancer: impact on outcomes of different treatment strategies. A multicenter study. Lung Cancer. 2011;72:340–347.
    1. Reynen K, Köckeritz U, Strasser R. Metastases to the heart. Ann Oncol. 2004;15:375–381.

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