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Review
. 2025:1467:21-26.
doi: 10.1007/978-3-031-72230-1_5.

Electroretinography

Julie Shabto  1 , Stephen Tsang  2 , Tarun Sharma  1 , Vlad Diaconita  1
Affiliations
Review

Electroretinography

Julie Shabto et al. Adv Exp Med Biol. 2025.

Abstract

The electroretinogram (ERG) is used to measure electrical activity of various cell types in several layers of the retina, including rods, cones, inner retinal cells, and ganglion, in response to a light stimulus. ERG therefore provides objective information about visual system function and can provide diagnostic information for inherited and acquired retinal disorders. It can also provide objective measurements of disease progression, including development of retinal toxicity due to medications, and treatment response.

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References

Further Reading

    1. Holder GE. Pattern electroretinography (PERG) and an integrated approach to visual pathway diagnosis. Prog Retin Eye Res. 2001;20:531–61.
    1. Jiang X, Mahroo OA. Negative electroretinograms: genetic and acquired causes, diagnostic approaches and physiological insights. Eye. 2021;35:2419-2437.
    1. Sustar M, Holder GE, Kremers J, Barnes CS, Lei B, Khan NW, Robson AG. ISCEV extended protocol for the photopic on-off ERG. Doc Ophthalmol. 2018;136:199-206.
    1. Robson AG, Frishman LJ, Grigg J, Hamilton R, Jeffrey BG, Kondo M, Li S, McCulloch DL, International Society for Clinical Electrophysiology of Vision. ISCEV Standard for full-field clinical electroretinography (2022 update). Doc Ophthalmol. 2022;144:165–177.
    1. Robson AG, Nilsson J, Li S, Jalali S, Fulton AB, Tormene AP, Holder GE, Brodie SE. ISCEV guide to visual electrodiagnostic procedures. Doc Ophthalmol. 2018;136:1-26.

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