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. 2025:1467:245-247.
doi: 10.1007/978-3-031-72230-1_48.

Syphilis

Kristina J Hartung  1   2 , Stephen H Tsang  3 , Tarun Sharma  4 , Vlad Diaconita  4
Affiliations

Syphilis

Kristina J Hartung et al. Adv Exp Med Biol. 2025.

Abstract

Syphilis is known as the "great imitator" and can occur in any stage of the disease and involve virtually any ocular structure, causing conjunctivitis, conjunctival chancre, episcleritis, scleritis, interstitial keratitis, uveitis, chorioretinitis, retinitis, vasculitis, neuroretinitis, papillitis, retrobulbar neuritis, papilledema, ocular motor nerve palsies, and Argyll Robertson pupil.

Keywords: Phenocopies; Syphilis.

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References

Further Reading

    1. Gass JD, Braunstein RA, Chenoweth RG. Acute syphilitic posterior placoid chorioretinitis. Ophthalmology 1990;97(10):1288-97.
    1. Pichi F, Ciardella AP, Cunningham ET Jr, Morara M, Veronese C, Jumper JM, Albini TA, Sarraf D, McCannel C, Voleti V, Choudhry N, Bertelli E, Giuliari GP, Souied E, Amer R, Regine F, Ricci F, Neri P, Nucci P. Spectral domain optical coherence tomography findings in patients with acute syphilitic posterior placoid chorioretinopathy. Retina 2014;34(2):373-84.
    1. Vaze A, De Angelis RE, Simões M, Arantes TE, Moreto R, Oliver GF, Smith JR, Furtado JM. Optical coherence tomography findings in ocular syphilis involving the posterior segment of the eye. Ocul Immunol Inflamm 2021; 15:1-7.
    1. Zhang T, Zhu Y, Xu G. Clinical features and treatments of syphilitic uveitis: a systematic review and meta-analysis. J Ophthalmol 2017; 6594849.

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