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. 2025 Jul 30.
doi: 10.1007/s15010-025-02617-6. Online ahead of print.

An unusual case of necrotizing pneumonia in a healthy apnea diver

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An unusual case of necrotizing pneumonia in a healthy apnea diver

Christian Beyer et al. Infection. .

Abstract

We report a case of necrotizing pneumonia caused by hypervirulent Klebsiella pneumoniae in an athletic, 54-year-old apnea diver. Since hypervirulent Klebsiella pneumoniae strains prevail in Southeast Asia and are mainly associated with "invasive liver abscess syndrome", we considered and tested for hypervirulence only when the necrotizing pneumonia turned out to be refractory to initial antibiotic treatment. Although the hypervirulent Klebsiella pneumoniae strain in our patient did not show multi-drug resistance, a total of 6 months of high-dose antibiotic therapy was necessary to cure the infection.

Keywords: Difficult-to-treat; Hypervirulent Klebsiella pneumoniae; Pneumonia; Virulence factors.

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Conflict of interest statement

Declarations. Consent to participate: Not applicable (case report). Consent to publish: The participant has consented to the submission of the case report to the journal. Competing interests: The authors declare no competing interests.

References

    1. Choby JE, Howard-Anderson J, Weiss DS. Hypervirulent Klebsiella pneumoniae - clinical and molecular perspectives. J Intern Med. 2020;287(3):283–300. https://doi.org/10.1111/joim.13007 - DOI
    1. Kocsis B. Hypervirulent Klebsiella pneumoniae: an update on epidemiology, detection and antibiotic resistance. Acta Microbiol Immunol Hung. 2023;70(4):278–87. https://doi.org/10.1556/030.2023.02186 - DOI
    1. Russo TA, Marr CM. Hypervirulent Klebsiella pneumoniae. Clin Microbiol Rev. 2019;32(3). https://doi.org/10.1128/CMR.00001-19
    1. Zhu J, Wang T, Chen L, Du H. Virulence factors in hypervirulent Klebsiella pneumoniae. Front Microbiol. 2021;12:642484. https://doi.org/10.3389/fmicb.2021.642484 - DOI
    1. Siu LK, Yeh KM, Lin JC, Fung CP, Chang FY. Klebsiella pneumoniae liver abscess: a new invasive syndrome. Lancet Infect Dis. 2012;12(11):881–7. https://doi.org/10.1016/S1473-3099(12)70205-0 - DOI

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