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. 2025 Jan-Dec:16:21501319251359547.
doi: 10.1177/21501319251359547. Epub 2025 Jul 30.

Use of Pharmacists and Collaborative Practice Agreements to Treat Hepatitis C: A Survey of Primary Care Clinicians in Washington State

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Use of Pharmacists and Collaborative Practice Agreements to Treat Hepatitis C: A Survey of Primary Care Clinicians in Washington State

Jocelyn R James et al. J Prim Care Community Health. 2025 Jan-Dec.

Abstract

Background: Collaborative care models that utilize pharmacists can expand hepatitis C (HCV) treatment access, but little is known about primary care provider (PCP) views on such models of care. We characterized PCP experiences of HCV treatment and assessed acceptability of leveraging pharmacists to treat HCV.

Methods: We surveyed a convenience sample of Washington (WA) State PCPs regarding HCV treatment, experience of collaborating with pharmacists, and comfort with pharmacists managing HCV care. We report summarized descriptive statistics of survey responses.

Results: Seventy-three PCPs completed the survey, 55% of whom prescribe buprenorphine for opioid use disorder. Nineteen percent directly treat HCV. Forty-five percent were aware of collaborative practice agreements (CPAs) and 22% reported interest in establishing a CPA to treat HCV. Most respondents were comfortable or extremely comfortable with pharmacists managing key elements of HCV care.

Conclusions: In a sample of WA State PCPs, of whom greater than half prescribe buprenorphine for OUD, fewer than 1 in 5 directly treat HCV. Comfort with pharmacists managing most components of HCV treatment was high, but a minority of PCPs were familiar with or interested in establishing CPAs. Additional efforts are needed to leverage pharmacists to treat HCV, including among people who use drugs.

Keywords: acceptability; collaborative practice agreement; hepatitis C; opioid related disorders; pharmacists.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

A bar chart shows comfort levels with 9 healthcare aspects related to hepatitis C management.
Figure 1.
Comfort with pharmacists managing key aspects of hepatitis C care (N = 73).
This bar chart illustrates the percentage of primary care clinicians’ concerns regarding hepatitis C care delivery by pharmacists under a Certified Pharmacist Assistant (CPA). The chart is segmented into five categories: Risk management, Care coordination/fractionation, Lack of compensation for the provider, Lack of time to coordinate care, and No concerns, with percentages ranging from 0% to 60% on the horizontal axis.
Figure 2.
Primary care clinician concerns about hepatitis C care delivery by pharmacists practicing under a CPA (N = 73)a. aChart shows percentage of participants who selected each response. Participants could select more than 1 response.

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