Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 May 29;7(8):101038.
doi: 10.1016/j.xkme.2025.101038. eCollection 2025 Aug.

Clinical Implications of Striated Nephrogram in Patients Receiving Immune Checkpoint Inhibitors for Cancer

Daiana Moreno  1 , Paul E Hanna  2 , Kavita Mistry  3 , Pedram Heidari  4 , Meghan E Sise  1 , Harish Seethapathy  1
Affiliations

Clinical Implications of Striated Nephrogram in Patients Receiving Immune Checkpoint Inhibitors for Cancer

Daiana Moreno et al. Kidney Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Striated nephrogram. Representative images [Coronal (A), Axial (B)] showing striated nephrogram (arrows) in a 60- to 65-year-old woman, detected 12 weeks after the initiation of pembrolizumab for hepatocellular carcinoma.
Figure 2
Figure 2
Incidence and etiology of striated nephrogram in patients receiving ICIs. Abbreviations: AIN, acute interstitial nephritis; AKI, acute kidney injury; ATN, acute tubular necrosis; ICI, immune checkpoint inhibitor; UTI, urinary tract infection.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Seethapathy H., Herrmann S.M., Sise M.E. Immune checkpoint inhibitors and kidney toxicity: advances in diagnosis and management. Kidney Med. 2021;3(6):1074–1081. - PMC - PubMed
    1. Kitchlu A., Jhaveri K.D., Wadhwani S., et al. A systematic review of immune checkpoint inhibitor-associated glomerular disease. Kidney Int Rep. 2021;6(1):66–77. - PMC - PubMed
    1. Puzanov I., Diab A., Abdallah K., et al. Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. J Immunother Cancer. 2017;5(1):95. - PMC - PubMed
    1. Gosangi B., McIntosh L., Keraliya A., et al. Imaging features of toxicities associated with immune checkpoint inhibitors. Eur J Radiol Open. 2022;9 - PMC - PubMed
    1. Awiwi M.O., Abudayyeh A., Abdel-Wahab N., et al. Imaging features of immune checkpoint inhibitor-related nephritis with clinical correlation: a retrospective series of biopsy-proven cases. Eur Radiol. 2023;33(3):2227–2238. - PMC - PubMed

LinkOut - more resources