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. 2025 Sep;66(9):100870.
doi: 10.1016/j.jlr.2025.100870. Epub 2025 Jul 29.

The risk of going outside: Amino phospholipids in rheumatoid arthritis

Nicola Pozzi  1 , David A Ford  2
Affiliations

The risk of going outside: Amino phospholipids in rheumatoid arthritis

Nicola Pozzi et al. J Lipid Res. 2025 Sep.
No abstract available

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Conflict of interest statement

Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article.

Figures

Fig. 1
Fig. 1
Extracellular vesicles (EVs) increase thrombotic risk in rheumatic arthritis (RA). A: Levels of EVs are elevated in RA patients compared to healthy controls (HC). These EVs contain more (B) phosphatidylserine (PS), some of which are (C) externally facing. D: External-facing PS on EVs stimulates prothrombinase support, assembly of prothrombinase complex (PTC), and promotes thrombin generation, thereby increasing the risk of venous thromboembolism (VTE). Panels A, B, and C are from Figs. 1E, 1M, and 1K, respectively, of the work by Costa D. et al. (7).
See this image and copyright information in PMC

References

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