Commentary on acid suppression after esophageal atresia repair-Some infants do benefit

Affiliations

¹ Department of Pediatrics, Peyton Manning Children's Hospital, University of Florida School of Medicine, Evansville, Indiana, USA.
² Dayton Children's Hospital, Dayton, Ohio, USA.

Donald George et al. J Pediatr Gastroenterol Nutr. 2025 Oct.

. 2025 Oct;81(4):911-912.

doi: 10.1002/jpn3.70174. Epub 2025 Jul 31.

¹ Department of Pediatrics, Peyton Manning Children's Hospital, University of Florida School of Medicine, Evansville, Indiana, USA.
² Dayton Children's Hospital, Dayton, Ohio, USA.

No abstract available

Keywords: post surgical prophylaxis; proton pump inhibitor.

References

1. Bell JC, Baynam G, Bergman JEH, et al. Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs. Birth Def Res. 2021;113(12):945‐957. doi:10.1002/bdr2.1891
1. Comella A, Tan Tanny SP, Hutson JM, et al. Esophageal morbidity in patients following repair of esophageal atresia: a systematic review. J Pediatr Surg. 2021;56(9):1555‐1563. doi:10.1016/j.jpedsurg.2020.09.010
1. Krishnan U, Mousa H, Dall'oglio L, et al. ESPGHAN‐NASPGHAN guidelines for the evaluation and treatment of gastrointestinal and nutritional complications in children with esophageal atresia‐tracheoesophageal fistula. J Pediatr Gastroenterol Nutr. 2016;63:550‐570.
1. Wyllie T, Folaranmi E, Sekaran P, Watkins WJ, Chakraborty M. Prophylactic acid‐suppression medication to prevent anastomotic strictures after oesophageal atresia surgery: a systematic review and meta‐analysis. J Pediatr Surg. 2023;58:1954‐1962.
1. Dimitrov G, Aumar M, Duhamel A, Wanneveich M, Gottrand F. Proton pump inhibitors in esophageal atresia: a systematic review and meta‐analysis. J Pediatr Gastroenterol Nutr. 2024;78(3):457‐470. doi:10.1002/jpn3.12115