Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1985 Oct;20(4):421-4.
doi: 10.1111/j.1365-2125.1985.tb05089.x.

The effect of ultrasound on the percutaneous absorption of lignocaine

J C McElnay, M P Matthews, R Harland, D F McCafferty
Clinical Trial

The effect of ultrasound on the percutaneous absorption of lignocaine

J C McElnay et al. Br J Clin Pharmacol. 1985 Oct.

Abstract

The influence of ultrasound on the percutaneous absorption of lignocaine from a cream base was investigated in a double-blind cross-over trial in healthy volunteers. Mean data indicated that there was a slightly faster onset time for local anaesthesia when ultrasound was administered when compared with control values (no ultrasound). However, the differences were not statistically significant. Further controlled clinical studies are required into the effect of ultrasound on percutaneous absorption since the technique (phonophoresis) has been alleged to enhance percutaneous penetration of a number of drugs.

PubMed Disclaimer

References

    1. Phys Ther. 1966 Jan;46(1):18-26 - PubMed
    1. Phys Ther. 1982 Jan;62(1):32-3 - PubMed
    1. Phys Ther. 1975 Dec;55(12):1320-4 - PubMed
    1. Phys Ther. 1967 Jul;47(7):594-601 - PubMed

Publication types

LinkOut - more resources