Associations Between Blood Eosinophil Surface Proteins and Clinical Traits in Severe Asthma and Chronic Rhinosinusitis With Nasal Polyposis

Emeline Delaunay^{1

2}, Stephane Esnault^{1

2

3}, Arnaud Dendooven^{1

2}, Thomas Stoup⁴, Thibaut Vanderhaegen⁵, Louison Jan⁵, Laurine Cadart⁶, Cecile Chenivesse^{7

8}, Geoffrey Mortuaire^{1

5}, Guillaume Lefèvre^{1

2}

Affiliations

¹ Univ. Lille, INSERM, CHU Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
² CHU Lille, Institut D'immunologie, Médecine Interne et Immunologie Clinique, Lille, France.
³ Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
⁴ Univ. Lille, CHU Lille, Service de Pneumologie et Immuno-Allergologie, U1286 Inserm INFINITE, Univ. Lille, Institute for Translational Research in Inflammation, Lille, France.
⁵ Univ. Lille, CHU Lille, Service D'otorhinolaryngologie, U1286 Inserm INFINITE, Univ. Lille, Institute for Translational Research in Inflammation, Lille, France.
⁶ CHU Lille, Service de Biostatistique, Lille, France.
⁷ Univ. Lille, CHU Lille, CNRS, Inserm, Institut Pasteur Lille, U1019-UMR9017-CIIL-Centre D'infection et D'immunité de Lille, Lille, France.
⁸ CRISALIS (Clinical Research Initiative in Severe Asthma: A Lever for Innovation & Science), Toulouse, France.

Emeline Delaunay et al. Allergy. 2025.

. 2025 Aug 2.

doi: 10.1111/all.70001. Online ahead of print.

¹ Univ. Lille, INSERM, CHU Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
² CHU Lille, Institut D'immunologie, Médecine Interne et Immunologie Clinique, Lille, France.
³ Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
⁴ Univ. Lille, CHU Lille, Service de Pneumologie et Immuno-Allergologie, U1286 Inserm INFINITE, Univ. Lille, Institute for Translational Research in Inflammation, Lille, France.
⁵ Univ. Lille, CHU Lille, Service D'otorhinolaryngologie, U1286 Inserm INFINITE, Univ. Lille, Institute for Translational Research in Inflammation, Lille, France.
⁶ CHU Lille, Service de Biostatistique, Lille, France.
⁷ Univ. Lille, CHU Lille, CNRS, Inserm, Institut Pasteur Lille, U1019-UMR9017-CIIL-Centre D'infection et D'immunité de Lille, Lille, France.
⁸ CRISALIS (Clinical Research Initiative in Severe Asthma: A Lever for Innovation & Science), Toulouse, France.

No abstract available

Keywords: CRSwNP; disease severity; eosinophils; severe asthma; surface protein expression.

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