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Review
. 2025 Jul 18:38:13622.
doi: 10.3389/ti.2025.13622. eCollection 2025.

The Future of Pig Liver Xenotransplantation

Ahmad Karadagi  1   2 , Gabriel C Oniscu  1   2
Affiliations
Review

The Future of Pig Liver Xenotransplantation

Ahmad Karadagi et al. Transpl Int. .

Abstract

Recent technological advances in genetic engineering have led to a renewed interest in xenotransplantation. Milestones achievements in heart, kidney and more recently liver xenotransplantation raise the hope of an alternative source of organs and pave the way for first in human clinical trials. With these rapid developments, it is important to consider what may be the place of liver xenotransplantation in the treatment armamentarium and what are the challenges to achieve clinical liver xenotransplantation.

Keywords: auxiliary liver transplantation; cross circulation; decedent model; liver transplant; xenotransplantation.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

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