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Case Reports
. 2025 Jul 5;17(7):e87328.
doi: 10.7759/cureus.87328. eCollection 2025 Jul.

Acute Adenoviral Gastroenteritis Complicated by Interstitial Edematous Pancreatitis in an Adult Patient: A Rare Clinical Case With a Multidisciplinary Approach

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Case Reports

Acute Adenoviral Gastroenteritis Complicated by Interstitial Edematous Pancreatitis in an Adult Patient: A Rare Clinical Case With a Multidisciplinary Approach

Anastasiia K Shkvarok et al. Cureus. .

Abstract

Adenovirus F (type 40/41) is one of the most significant viral etiological agents of acute gastroenteritis in young children. This is a significant and growing cause of pediatric gastroenteritis worldwide, particularly in children under the age of five. However, in rare cases, it may also lead to clinically significant illness in adults. The clinical case we present describes the course of acute adenoviral gastroenteritis complicated with acute pancreatitis and a pronounced intoxication syndrome in a 24-year-old woman from Ukraine.

Keywords: acute intestinal infection; adenovirus f; adenovirus infection; diarrhea; gastroenteritis; pancreatitis; vomiting.

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Conflict of interest statement

Human subjects: Informed consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Ultrasound examination of the pancreas (the pancreatic head)
The pancreatic head exhibits increased echogenicity with blurred contours, indicative of tissue edema. The structure measures 36.8 mm in transverse section (blue dashed line; Dist A), suggesting volume increase due to the inflammatory process. Surrounding tissues show diffuse decreased echogenicity, typical of edema, with hypoechoic areas that may correspond to inflammatory infiltrates. No distinct signs of necrosis or pseudocysts are present.
Figure 2
Figure 2. Ultrasound examination of the pancreas (the body of the pancreas)
The body of the pancreas is visualized as a homogeneous structure with medium echogenicity and well-defined, smooth contours. The structure measures 25.4 mm in transverse section (blue dashed line; Dist A), which is consistent with the normal range for this anatomical region. The surrounding tissues exhibit normal echogenicity without signs of diffuse changes or focal lesions. No visible pathological inclusions, such as cystic or solid masses, are present.

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References

    1. Kajon AE, Weinberg JB, Spindler KR. Reference Module in Biomedical Sciences. New York City, NY: Elsevier; 2019. Adenoviruses.
    1. Epidemiological trends of diarrheal viruses in central and western Kenya before and after rotavirus vaccine introduction. Mutua MM, Kathiiko C, Wachira MN, et al. Trop Med Health. 2025;53:60. - PMC - PubMed
    1. Human adenoviruses in children with gastroenteritis: a systematic review and meta-analysis. Khales P, Razizadeh MH, Ghorbani S, et al. BMC Infect Dis. 2024;24:478. - PMC - PubMed
    1. Pediatric acute gastroenteritis associated with adenovirus 40/41 in low-income and middle-income countries. Lee B, Damon CF, Platts-Mills JA. Curr Opin Infect Dis. 2020;33:398–403. - PMC - PubMed
    1. Etiology of diarrhea requiring hospitalization in Bangladesh by quantitative polymerase chain reaction, 2014-2018. Taniuchi M, Islam K, Sayeed MA, et al. Clin Infect Dis. 2021;73:0–9. - PMC - PubMed

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