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. 2025 Sep;31(9):1718-1728.
doi: 10.3201/eid3109.250554. Epub 2025 Aug 5.

Epidemiology of Chikungunya Hospitalizations, Brazil, 2014-2024

Vaneide Daciane Pedí, Denise Lopes Porto, Wagner de Jesus Martins, Giovanny Vinícius Araújo de França

Epidemiology of Chikungunya Hospitalizations, Brazil, 2014-2024

Vaneide Daciane Pedí et al. Emerg Infect Dis. 2025 Sep.

Abstract

We describe 7,421 chikungunya hospitalizations in Brazil covered by the country's unified health system during 2014-2024. Most (43.2%) hospitalizations occurred in 2016 and 2017, reaching 0.72 (95% CI 0.69-0.76) hospitalizations/100,000 population in 2016. Hospitalizations were more frequent among persons who were female (55.8%), identifying as brown or black (63.5%), and 1-19 years of age (31.4%). Intensive care unit admissions occurred in 1.4% of cases, predominantly among children <5 and adults >85 years of age. The overall in-hospital case-fatality rate was 1.1%, which increased substantially with age, reaching 11.5% among patients >90 years of age and 14.1% among men 85-89 years of age. Patients admitted to the intensive care unit had a case-fatality rate of 21.1%. The total cost of chikungunya hospitalizations was US $560,746 (US $76.26 per patient). Our findings provide insights for surveillance of the most severe chikungunya cases.

Keywords: Brazil; Chikungunya virus; chikungunya fever; hospitalization; vector-borne infections; viruses; zoonoses.

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Figures

Figure 1
Figure 1
Regions and federal units referenced in study of epidemiology of chikungunya hospitalizations, Brazil, 2014–2024.
Figure 2
Figure 2
Number of hospitalizations per year in study of epidemiology of chikungunya hospitalizations, Brazil, 2014–2024. A) Total number of hospitalizations per year; B) number of hospitalizations per year by region.
Figure 3
Figure 3
Annual hospitalization rates per region from study of epidemiology of chikungunya hospitalizations, Brazil, 2014–2024.
See this image and copyright information in PMC

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