[Research progress of volatile organic compound exposure and diabetes mellitus including its complications]
- PMID: 40764251
- DOI: 10.3760/cma.j.cn121094-20240205-00048
[Research progress of volatile organic compound exposure and diabetes mellitus including its complications]
Abstract
Volatile organic compounds (VOCs) are a type of organic compounds that exist in the form of vapor in the air at room temperature, and are common pollutants in industrial production and living environments. The health hazards caused by exposure to VOCs are gradually gaining recognition and social attention. At present, the research on the harm of VOCs to human health mainly involves the respiratory system, cardiovascular system and nervous system. However, in recent years, people have realized that VOCs can induce glucose metabolism disorder through insulin resistance, oxidative stress and oxidative damage, inflammatory reaction and liver damage, leading to increased blood sugar and increased potential risk of diabetes, and even increased the risk of complications of diabetes. This review summarizes the epidemiology and related mechanisms of VOCs, diabetes and its complications, providing a reference for effective prevention and control of VOC induced diabetes.
挥发性有机化合物（volatile organic compounds，VOCs）是一类常温下以蒸气形式存在于空气的有机化合物，是工业生产和生活环境中常见污染物。接触VOCs导致的健康危害逐步得到认识和社会的关注。目前有关VOCs对人类健康危害的研究主要涉及呼吸系统、心血管系统和神经系统，然而VOCs可通过胰岛素抵抗、氧化应激和氧化损伤、炎症反应和肝脏损伤等途径诱发葡萄糖代谢紊乱，导致血糖升高和糖尿病潜在风险升高，甚至增加糖尿病并发症的发生风险。本文综述总结了VOCs与糖尿病及其并发症的流行病学和相关机制研究，为有效防控VOCs所致糖尿病提供参考。.
Keywords: Complication; Diabetes mellitus; Epidemiology; Mechanism; Volatile organic compounds.
