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. 2025 Jul 31;10(3):V27-V30.
doi: 10.21980/J8KW8V. eCollection 2025 Jul.

A Case Report of Calciphylaxis

Affiliations

A Case Report of Calciphylaxis

Kim Hoang et al. J Educ Teach Emerg Med. .

Abstract

Calciphylaxis is a rare condition that is not well understood but is known to carry significant morbidity and mortality. We present a 44-year-old male with a history of end-stage renal disease on dialysis complaining of increasingly painful chronic wounds. The patient's physical exam was remarkable for ulcerated, bilateral anterior leg wounds with large areas of eschar along with purulent drainage. He was admitted to the hospital for intravenous antibiotics, wound care, and specialist consultation for treatment of calciphylaxis. This case report provides an overview of the key clinical features of calciphylaxis and reviews potential treatment strategies for this life-threatening condition.

Topics: Calciphylaxis, chronic kidney disease, end-stage renal disease, wound infection, wound care.

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Video Links: https://youtu.be/3dkK9hj2hQs https://youtu.be/Gzl_h8ywQiM

References

    1. Nigwekar SU, Kroshinsky D, Nazarian RM, et al. Calciphylaxis: risk factors, diagnosis, and treatment. Am J Kidney Dis. 2015;66(1):133–146. doi: 10.1053/j.ajkd.2015.01.034. - DOI - PMC - PubMed
    1. Angelis M, Wong LL, Myers SA, Wong LM. Calciphylaxis in patients on hemodialysis: A prevalence study. Surgery. 1997;122(6):1083–1090. doi: 10.1016/S0039-6060(97)90212-9. - DOI - PubMed
    1. Brandenburg VM, Cozzolino M, Ketteler M. Calciphylaxis: a still unmet challenge. J Nephrol. 2011;24(2):142–148. doi: 10.5301/jn.2011.6366. - DOI - PubMed
    1. Weenig RH, Sewell LD, Davis MD, McCarthy JT, Pittelkow MR. Calciphylaxis: Natural history, risk factor analysis, and outcome. J Am Acad Dermatol. 2007;56(4):569–579. doi: 10.1016/j.jaad.2006.08.065. - DOI - PubMed
    1. Portales-Castillo I, Kroshinsky D, Malhotra CK, et al. Calciphylaxis-as a drug induced adverse event. Expert Opin Drug Saf. 2019;18(1):29–35. doi: 10.1080/14740338.2019.1559813. - DOI - PubMed