Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Aug:35:151524.
doi: 10.1016/j.sempedsurg.2025.151524. Epub 2025 Aug 5.

Advancing advocacy for evidence-based opioid stewardship

Affiliations
Review

Advancing advocacy for evidence-based opioid stewardship

Jenna S Lee et al. Semin Pediatr Surg. 2025 Aug.

Abstract

Opioids are frequently prescribed for postsurgical and acute pain management for both adults and children. However, research has shown that overprescription and improper handling of these medications contribute to problematic substance use, dependency, and overdose among the pediatric population. Despite increased awareness and efforts to mitigate the opioid epidemic, challenges persist, including inconsistent prescribing practices, inadequate education on safe disposal practices, gaps in prescription monitoring systems, and barriers to naloxone availability. In this review, we will highlight actionable steps and strategies for advocacy and intervention to reduce the burden of the opioid crisis in children and adolescents. Key topics include the critical role of opioid stewardship when managing postoperative pain, the importance of family engagement and education on safe disposal methods, the ongoing challenges of safe prescribing and monitoring, and opportunities to extend substance use screening and treatment referral for injured adolescents. Additionally, we will highlight policy recommendations to promote equitable access and availability of harm reduction tools such as naloxone. These strategies, if implemented together, can significantly reduce the risks associated with pediatric opioid use and mitigate the impact of the opioid epidemic on children and adolescents.

Keywords: Naloxone; Opioid; Opioid stewardship; Overdose; Pain.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

MeSH terms

LinkOut - more resources