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Review
. 2025 Sep;52(3):565-580.
doi: 10.1016/j.ogc.2025.05.012. Epub 2025 Jul 3.

Pregnancy as a Window to Future Health

Alicia Mandujano  1 , Michele R Lauria  2 , Thaddeus P Waters  3
Affiliations
Review

Pregnancy as a Window to Future Health

Alicia Mandujano et al. Obstet Gynecol Clin North Am. 2025 Sep.

Abstract

Pregnancy can be a window into a woman's long-term cardiovascular and metabolic health. Adverse pregnancy outcomes (APOs), such as hypertensive disorders of pregnancy, gestational diabetes, preterm birth, fetal growth restriction or small-for-gestational age infants, and abruption, have been demonstrated to increase a woman's future morbidity and mortality. Women identified to be at high risk for future cardiometabolic dysfunction based on their APOs should receive regular cardiovascular risk assessments and treatment with their primary care provider and/or cardiologist to optimize long-term health outcomes.

Keywords: Abruption; Adverse pregnancy outcomes; Fetal growth restriction; Gestational diabetes; Hypertensive disorders of pregnancy; Maternal health; Preterm birth.

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Conflict of interest statement

Disclosure A. Mandujano, MD: None. M.R. Lauria, MD, MS:None. T.P. Waters, MD: Dr Waters is the site PI for a PCORI grant (96,773). This study is evaluating novel models for clinical care postpartum to improve health care outcomes including hypertension and mental health. Dr Waters is also a committee member for the New York State Maternal Mortality Review Board (MMRB) and serves on the New York State Task Force for Maternal Health and on the steering committee for this as well. Dr Waters has previously received funding from the Center for Disease Control for evaluating post-delivery hyperglycemia in patients with gestational diabetes.