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. 1977 Jun 24;24(2):147-56.
doi: 10.1007/BF02889275.

Observations on the association of annulate lamellae with vinblastine-induced paracrystals in tumour cells in vitro

J Chemnitz, K Salmberg, F Bierring

Observations on the association of annulate lamellae with vinblastine-induced paracrystals in tumour cells in vitro

J Chemnitz et al. Virchows Arch B Cell Pathol. .

Abstract

Tumour cells in vitro responded to prolonged treatment with colchicine with the formation of annulate lamellae. Following the colchicine treatment, paracrystals were induced with vinblastine. A close association of annulate lamellae with vinblastine-induced crystals was observed. The hypothesis that annulate lamellae and the related unclear membrane with the pore complexes may play a role in the control of the cytoplasmic microtubule complex is discussed.

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